1620161-80-9Relevant academic research and scientific papers
Phosphonopeptides revisited, in an era of increasing antimicrobial resistance
Anderson, Rosaleen J.,Bedernjak, Alexandre F.,Cummings, Stephen P.,Day, Kathryn M.,Gray, Mark,Jones, Amanda L.,Marrs, Emma C. L.,Perry, John D.,Varadi, Linda
, (2020)
Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
The effect of monosaccharides on self-assembly of benzenetricarboxamides
Wang, Jue,Qi, Wenjing,Chen, Guosong
supporting information, p. 587 - 591 (2019/01/04)
The interaction between monosaccharides exhibits an important role in the assembly of monosaccharide-containing molecules. In this work, three common monosaccharides, glucose, galactose and mannose, are employed to investigate the effect of monosaccharide on the self-assembly of benzenetricarboxamide (BTA) core-containing molecules. In the presence of monosaccharides, three benzenetricarboxamide derivatives aggregate into different ordered structures. When alanine linkers are introduced to these molecules between the core and the monosacchride, morphologies of three types of monosaccharide BTAs turned to disordered, meanwhile their structures become similar with the increase of the length of alanine linkers, indicating the disappearance of the monosaccharide effects.
Facile and mild synthesis of linear and cyclic peptides via thioesters
Agrigento, Paola,Albericio, Fernando,Chamoin, Sylvie,Dacquignies, Isabelle,Koc, Halil,Eberle, Martin
supporting information, p. 3922 - 3925 (2014/08/18)
Thioester-mediated peptide bond formation has recently garnered a lot of attention, most notably in its relevance to condensation of large peptide fragments. Herein, a simple and general ligation method for the preparation of linear and cyclic peptides, starting from peptide thioester, mainly p-chlorophenyl, precursors is reported. The inherent advantages of this method are the low epimerization, reduced dimerization, use of mild reaction conditions, and elimination of superfluous coupling reagents.
