1620162-53-9

Upstream product

• 1620161-68-3 (S)-S-(4-nitrophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate 
• 1620161-69-4 (S)-S-phenyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate 
• 1620161-70-7 (S)-S-(4-methoxyphenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate 
• 27317-69-7 N-tert-butoxycarbonyl-L-alanyl-L-alanine 
• 1620161-71-8 (S)-S-(4-chlorophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate 
• 1620161-72-9 (S)-S-(2-chlorophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate 
• 1620161-73-0 (S)-S-(3-chlorophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate 
• 1620161-74-1 (S)-S-(4-fluorophenyl) 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanethioate 
• 201289-18-1 (S)-4-nitrophenyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanoate 
• 1620161-80-9 (S)-perfluorophenyl 2-((S)-2-((tert-butoxycarbonyl)amino)propanamido)propanoate 
• 1620161-81-0 (6S,9S,15S,18S)-18-(4-hydroxybenzyl)-15-isobutyl-2,2,6,9-tetramethyl-4,7,10,13,16-pentaoxo-3-oxa-5,8,11,14,17-pentaazanonadecan-19-oic acid 
• 106-54-7 p-Chlorothiophenol 

Downstream Products

• 1620162-23-3 cyclo[-Ala-Ala-Gly-Leu-Tyr-] 
• 1620162-64-2 C₄₆H₆₆N₁₀O₁₂ 
• 1620162-11-9 C₂₉H₃₈ClN₅O₆S 

Relevant academic research and scientific papers

Facile and mild synthesis of linear and cyclic peptides via thioesters

Thioester-mediated peptide bond formation has recently garnered a lot of attention, most notably in its relevance to condensation of large peptide fragments. Herein, a simple and general ligation method for the preparation of linear and cyclic peptides, starting from peptide thioester, mainly p-chlorophenyl, precursors is reported. The inherent advantages of this method are the low epimerization, reduced dimerization, use of mild reaction conditions, and elimination of superfluous coupling reagents.