1621-55-2

Basic information

• Product Name: 3'-HYDROXYFLAVANONE
• Synonyms: 3'-HYDROXYFLAVANONE;HYDROXYFLAVANONE, 3';(3R*)-2,3-Dihydro-3-hydroxy-2-phenyl-4H-1-benzopyran-4-one;2,3-Dihydro-3-hydroxy-2-phenyl-4H-1-benzopyran-4-one;2,3-Dihydroflavonol;2-Phenyl-3-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one;Flavanonol
• CAS NO: 1621-55-2
• Molecular Formula: C₁₅H₁₂O₃
• Molecular Weight: 240.25
• Product Categories: Flavanones
• Mol File: 1621-55-2.mol
• Article Data: 16

Chemical Properties

• Melting Point: 139-141℃
• Boiling Point: 441.6°Cat760mmHg
• Flash Point: 171.4°C
• Appearance: /
• Density: 1.298g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3'-HYDROXYFLAVANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-HYDROXYFLAVANONE(1621-55-2)
• EPA Substance Registry System: 3'-HYDROXYFLAVANONE(1621-55-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 1621-55-2(Hazardous Substances Data)

Usage

General Description

3'-Hydroxyflavanone is a natural chemical compound belonging to the flavanone class of flavonoids. It is commonly found in various plants and fruits, including citrus fruits and tomatoes. 3'-HYDROXYFLAVANONE has been the subject of scientific research because of its potential health benefits, including antioxidant, anti-inflammatory, and anticancer properties. It has also shown potential for use in skincare products due to its ability to protect against UV-induced skin damage. Additionally, 3'-hydroxyflavanone has been studied for its potential to improve glucose metabolism and insulin sensitivity, making it a topic of interest in the field of diabetes research. Overall, 3'-hydroxyflavanone is a promising natural compound with a range of potential health benefits.

Upstream product

• 487-26-3 Flavanone 
• 129878-47-3 (E)-2'-hydroxychalcone epoxide 
• 888-12-0 (E)-2'-hydroxy-chalcone 
• 1621-55-2 rac-trans-3-hydroxy-2-phenyl-3,4-dihydro-2H-chromen-4-one 
• 57043-45-5 trans-3-acetoxyflavanone 
• 644-78-0 2-hydroxychalcone 
• 149-73-5 trimethyl orthoformate 
• 138610-97-6 4-acetoxy-2-phenyl-2H-1-chromene 
• 94137-50-5 cis-3-hydroxyflavanone dimethyl acetal 
• 25518-22-3 (2-hydroxy-phenyl)-(3-phenyl-oxiranyl)-methanone 
• 118-93-4 o-hydroxyacetophenone 
• 100-52-7 benzaldehyde 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 40524-63-8 2'-O-methoxymethylchalcone 

Downstream Products

• 577-85-5 3-hydroxyflavone 
• 94460-26-1 (+/-)-trans-3-hydroxy-2-phenyl-chroman-4-one semicarbazone 
• 94871-82-6 (+/-)-trans-3-hydroxy-2-phenyl-chroman-4-one-phenylhydrazone 
• 17044-60-9 (+/-)-trans-3-hydroxy-2-phenyl-chroman-4-one oxime 
• 1086-73-3 (2R^*,3S^*,4R^*)-flavan-3,4-diol 
• 70460-60-5 2-phenyl-chroman-3,4-dione 
• 1621-55-2 rac-trans-3-hydroxy-2-phenyl-3,4-dihydro-2H-chromen-4-one 
• 1621-55-2 rac-trans-3-hydroxyflavanone 
• 97618-71-8 (+/-)-4c-Amino-2r-phenyl-chroman-3t-ol 
• 103165-66-8 (+/-)-3t,4c-Bis-(4-nitro-benzoyloxy)-2r-phenyl-chroman 
• 139061-55-5 spiro<5-acetamido-3-acetyl-2,3-dihydro-1,3,4-thiadiazole-2,4'-trans-3'-acetoxyflavan> 
• 57043-45-5 trans-3-acetoxyflavanone 
• 20754-85-2 C₂₉H₂₂O₅ 
• 487-26-3 Flavanone 

Relevant articles and documents

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Design, synthesis and anti-inflammatory activity of dihydroflavonol derivatives

Thirty dihydroflavonol derivatives (D1–D30) were designed and synthesized, meanwhile the synthesized compounds were characterized on the basis of spectroscopic analyzes. Their inhibitory activity against the pro-inflammatory inducible interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in lipopolysaccharide (LPS)-stimulated murine RAW 264.7 macrophages were evaluated and showed various efficiency. Compounds D1–D30 showed no toxic effects on RAW 264.7 cells at the concentration 20 μM; among them, compounds D9, D13, and D19 exhibited best anti-inflammatory activity through decreasing IL-1β, IL-6, and TNF-α. Furthermore, their structure–activity relationships were discussed preliminarily.

Hydromagnesite as an efficient recyclable heterogeneous solid base catalyst for the synthesis of flavanones, flavonols and 1,4-dihydropyridines in water

A form of hydromagnesite (HM) with flower-like thin-sheet morphology was synthesized by an environmentally benign approach using simple conventional heating at moderate temperature without using any template in water as medium. The versatility of this HM catalyst was studied in the synthesis of flavanones, flavonols and the multicomponent synthesis of 1,4-dihydropyridines in water. The recyclability of catalyst was studied for six times and there was no appreciable loss in its catalytic activity. Copyright

Facile epoxidation of α,β-unsaturated ketones with cyclohexylidenebishydroperoxide

Cyclohexylidenebishydroperoxide was successfully used as the oxygen source for the oxidation of α,β-unsaturated ketones for the first time. The corresponding epoxides were obtained in excellent yields under the Weitz-Scheffer reaction conditions.