162221-97-8Relevant articles and documents
Synthesis of 1,2,4-Triazoles via Oxidative Heterocyclization: Selective C-N Bond over C-S Bond Formation
Gogoi, Anupal,Guin, Srimanta,Rajamanickam, Suresh,Rout, Saroj Kumar,Patel, Bhisma K.
, p. 9016 - 9027 (2015/09/28)
The higher propensity of C-N over C-S bond forming ability was demonstrated, through formal C-H functionalization during the construction of 4,5-disubstituted 1,2,4-triazole-3-thiones from arylidenearylthiosemicarbazides catalyzed by Cu(II). However, ster
Synthesis of new 1,2,4-Triazole-5-thiones and their thioglycoside derivatives as potential antibacterial agents
Dilmaghani, Karim Akbari,Nasuhi Pur, Fazel,Jazani, Nima Hoseini,Alavi, Asma,Niknam, Zahra,Mirfakhraee, Farrin
, p. 81 - 87 (2014/01/06)
Abstract The glycosylation of 1,2,4-triazole-5-thiones has been performed with peracetylated β-pyranosyl bromide in the presence of potassium carbonate. The synthesized compounds were tested for their antimicrobial activity against bacterial (Gram-negative and Gram-positive) and yeasts strains in vitro. The synthetic compounds showed different inhibition zones against tested bacterial and yeasts strains. Among them, compounds which possessed 2-furyl and p-bromophenyl moieties showed the best results against Acinetobacter calcoaceticus ATCC 23055.
Synthesis and tuberculostatic activity of some 2-piperazinmethylene derivatives 1,2,4-triazole-3-thiones
Foks, Henryk,Janowiec, Mieczyslaw,Zwolska, Zofia,Augustynowicz-Kopec, Ewa
, p. 537 - 543 (2007/10/03)
The Mannich reaction's products of 1,2,4-triazole-3-thiones, substituted in position 4 (with ethyl, allyl, phenyl, Ph-4-Br) or 5 (with phenyl, Ph-4-OH, Ph-3,4,5-(OMe)3, 2-phenyl) were obtained. Their amino-components were 1-phenylpiperazine, 1-