162356-20-9Relevant academic research and scientific papers
Synthesis of Chiral Bicyclic Lactams Using Ring Closure Metathesis: Synthesis of (-)-Coniceine and (S)-Pyrrolam A
Arisawa, Mitsuhiro,Takezawa, Emiko,Nishida, Atsushi,Mori, Miwako,Nakagawa, Masako
, p. 1179 - 1180 (1997)
Chiral (-)-coniceine and (S)-pyrrolam A were synthesized from dienes prepared from L-proline by ring closure metathesis.
Benzotriazole-Mediated Stereoselective Olefination of Carboxylic Esters: Transformation of α-Amino Acid Esters into Chiral Allylamines
Katritzky, Alan R.,Cheng, Dai,Li, Jianqing
, p. 3438 - 3444 (2007/10/03)
Diastereoselective trans-olefinations of carboxylic esters 3a-h have been accomplished using benzylic or allylic benzotriazole derivatives 1a-e to prepare α-(benzotriazol-1-yl) ketones 4a-i, for the subsequent reduction of 4a-i, and finally for low-valent titanium-effected dehydroxybenzotriazolylation.1 N-Protected α-amino acid esters 9a-c and 15 thus give allylamines 13a-e and 19 with virtually full retention of chirality. Mechanistic aspects of the dehydroxybenzotriazolylation are discussed.
Stereochemical consequences of the Lewis acid-promoted 3-aza-cope rearrangement of N-alkyl-N-allyl enamines
Cook, Ggregory R.,Stille, John R.
, p. 4105 - 4124 (2007/10/02)
Internal and relative asymmetric induction were examined for the electrophile promoted 3-aza-Cope rearrangement of substituted N-alkyl-N-allyl enamines. In general, internal asymmetric induction was highly variable, and was dependent both upon the nature
