162600-01-3

Basic information

• Product Name: (1S,2R,3R)-1-(2-furyl)-2,3-isopropylidenyloxy-3-phenyl-1-propanol
• Synonyms: (1S,2R,3R)-1-(2-furyl)-2,3-isopropylidenyloxy-3-phenyl-1-propanol
• CAS NO: 162600-01-3
• Molecular Weight: 274.317
• Mol File: 162600-01-3.mol

Chemical Properties

• CAS DataBase Reference: (1S,2R,3R)-1-(2-furyl)-2,3-isopropylidenyloxy-3-phenyl-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R,3R)-1-(2-furyl)-2,3-isopropylidenyloxy-3-phenyl-1-propanol(162600-01-3)
• EPA Substance Registry System: (1S,2R,3R)-1-(2-furyl)-2,3-isopropylidenyloxy-3-phenyl-1-propanol(162600-01-3)

Safety Data

• Hazardous Substances Data: 162600-01-3(Hazardous Substances Data)

Upstream product

• 110-00-9 furan 
• 130718-77-3 (4R,5R)-cis-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-carbaldehyde 
• 2786-02-9 2-lithiofuran 
• 221108-29-8 (4R,5R)-2,2-dimethyl-4-(2-furoyl)-5-phenyl-1,3-dioxolane 
• 21915-53-7 (2R,3S)-(3-phenyloxiran-2-yl)methanol 
• 162600-00-2 ((4S,5R)-2,2-dimethyl-5-phenyl-1,3-dioxolan-4-yl)methanol 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 162466-15-1 (2S,3R)-2,3-isopropylidenyloxy-3-phenylpropanyl tert-butyldiphenylsilyl ether 
• 162466-13-9 (2S,3R)-2-hydroxy-3-acetoxyl-3-phenylpropanyl tert-butyldiphenylsilyl ether 
• 162466-14-0 (2S,3R)-2,3-dihydroxy-3-phenylpropanyl tert-butyldiphenylsilyl ether 
• 163748-92-3 Acetic acid (2S,3R)-2,3-dihydroxy-3-phenyl-propyl ester 
• 162466-12-8 (2S,3R)-3-acetoxyl-3-phenyl-1,2-propanediol 

Downstream Products

• 136778-39-7 (+)-goniofufurone 
• 96405-62-8 (5S,6R)-6-[(1S,2R)-1-(benzyloxy)-1,2-dihydroxy-2-phenylethyl]-5-hydroxy-5,6-dihydro-2H-pyran-2-one 
• 144429-71-0 (6R,7R,8R)-goniodiol-8-monoacetate 
• 136778-40-0 7,8-di-O-acetyl-goniodiol 
• 163630-06-6 (6R,4'S,5'R)-6-(2',2'-dimethyl-5'-phenyl-[1',3']dioxolan-4'-yl)-5,6-dihydropyran-2-one 
• 162466-16-2 (5S,6R)-5-hydroxy-6-<(1R,2R)-1,2-isopropylidenyloxy-2-phenylethyl>-5,6-dihydropyran-2-one 

Relevant articles and documents

Julia-Colonna asymmetric epoxidation of furyl styryl ketone as a route to intermediates to naturally-occurring styryl lactones

The enone 1 was oxidized stereoselectively using urea-hydrogen peroxide with polyleucine as the catalyst to give the epoxide 2 which was used to make (+)-goniotriol 7, (+)-goniofufurone 8, (+)-8-acetylgoniotriol 9 and goniopypyrone 10.

Asymmetric Total Synthesis of (+)-Goniotriol and (+)-Goniofufurone

Thr Enantioselective synthesis of two antitumor styryl lactones, (+)-goniotriol and (+)-goniofufurone, have been completed starting from cinnamyl alcohol in ten and eleven steps with an overall yield of 21percent and 12percent, respectively.

Total synthesis of the natural goniodiol-8-monoacetate from cinnamyl alcohol

The first total synthesis of goniodiol-8-monoacetate, using the Sharpless asymmetric epoxidation starting from cinnamyl alcohol in twelve steps with an overall yield of 7%, is achieved.