162635-53-2

Upstream product

• 116-11-0 2-Methoxypropene 
• 5336-08-3 D-Ribono-1,4-lactone 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 631920-67-7 4-(2,4-di-tert-butoxy-pyrimidin-5-yl)-6-(1-methoxy-1-methyl-ethoxymethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ol 
• 1224588-06-0 (3aR,6R,6aR)-6-(2-methoxypropan-2-yloxy)methyl-2,2-dimethyl-4-phenyltetrahydrofuro[3,4-d][1,3]dioxol-4-ol 
• 1445-07-4 pseudouridine 
• 630104-54-0 (2S,3S,3aR,6S,7R,7aR)-7-azido-2-(2',4'-dimethoxypyrimidin-5'-yl)-6-methoxy-3-(p-methoxybenzyloxy)-hexahydro-2H-furo[3,2-b]pyran 
• 630104-53-9 (2S,3S,3aR,6R,7R,7aR)-7-azido-2-(2',4'-dimethoxypyrimidin-5'-yl)-6-hydroxy-3-(p-methoxybenzyloxy)-hexahydro-2H-furo[3,2-b]pyran 
• 630104-51-7 (2S,3S,4R,5R)-4-allyloxy-2-(2',4'-dimethoxypyrimidin-5'-yl)-3-(p-methoxybenzyloxy)-5-vinyltetrahydrofuran 
• 1054610-00-2 2,4-Dimethoxy-5-[(1aS,3aS,4S,5S,6aS,6bS)-4-(4-methoxy-benzyloxy)-hexahydro-1,3,6-trioxa-cyclopropa[e]inden-5-yl]-pyrimidine 
• 630104-50-6 (2S,3S,4R,5R)-5-(2',4'-dimethoxypyrimidin-5'-yl)-4-(4'-methoxybenzyloxy)-2-vinyltetrahydrofuran-3-ol 
• 630104-52-8 2,4-dimethoxy-5-[3,7-anhydro-5,6-dideoxy-2-O-para-methoxybenzyl-D-glycero-β-D-allo-hepto-5-enofuranosyl]pyrimidine 
• 630104-49-3 C₃₁H₅₂N₂O₉Si₂ 
• 630104-48-2 2,4-Dimethoxy-5-[(2S,3S,3aR,9aR)-5,5,7,7-tetraisopropyl-3-(4-methoxy-benzyloxy)-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl]-pyrimidine 

Relevant academic research and scientific papers

Easy access to C-glycosides from aldonolactones by a Claisen-type chain-extension reaction

Chain elongated 2,4-diuloses 2, 4, 6, 9-11, 24, 25 were conveniently obtained from the corresponding aldonolactones 1, 3, 5 by their reaction with carbonyl compounds in the presence of sodium hydride. These hemiacetalic products can be transformed into C-

A new route to some enantiomerically pure substituted morpholines from D-ribono- and D-gulono-1,4-lactones

D-Ribono-1,4-lactone, after acetalation, tritylation, and reduction, leads to a cyclization compound which gave with tosyl chloride 1,4-anhydro-2,3-O-isopropylidene-5-O-trityl-D-ribitol.The latter was transformed (acid hydrolysis, periodate oxidation, reduction, tritylation, and tosylation) into a ditosylated derivative 16, which was cyclized into morpholines by the action of primary amines.Acid hydrolysis, followed by acetylation, gives the (2S)-acetoxymethyl-4-isopropyltetrahydro-1,4-oxazine (21).A similar sequence has been applied to D-gulonolactone to give access to oxazines 33, 34, and 35. Keywords: Synthesis; D-Ribono-1,4-lactone; D-Gulono-1,4-lactone; Morpholine derivatives