1628191-38-7Relevant articles and documents
Synthesis of α -Ketoamides by Copper-Catalyzed Reactions of Phenylacetic Acids with N,N -Dialkylformamides
Zhang, Lanping,Pu, Junnan,Ren, Jiayu,Li, Zhengkai,Xiang, Haifeng,Zhou, Xiangge
, p. 1848 - 1856 (2015)
A new synthetic approach for α-ketoamides was achieved by copper-catalyzed coupling reactions between N,N-dialkylformamides and phenylacetic acids. A variety of substrates were well tolerated to give yields of 46-87% (17 examples). A 13C-labeli
Metal-Free C=C Double Bond Cleavage on Enaminones for the Synthesis of α-Ketoamides by Free-Radical Aerobic Oxygenation
Yang, Yiming,Zhong, Guofeng,Fan, Junfen,Liu, Yunyun
supporting information, p. 4422 - 4425 (2019/06/24)
The tandem oxidation of the enaminone C=C double bond as well as subsequent C-N bond formation are realized under metal-free conditions by thermo-induced free radical transformation. In the presence of benzoyl peroxide (BPO) and N-iodosuccinimide (NIS), a
TBAI-catalyzed synthesis of α-ketoamides via sp3 C-H radical/radical cross-coupling and domino aerobic oxidation
Fan, Weizheng,Shi, Dongyang,Feng, Bainian
, p. 4638 - 4641 (2015/07/02)
A TBAI-catalyzed one-pot synthesis of α-ketoamides via sp3 C-H radical/radical cross-coupling and domino aerobic oxidation was developed. This synthesis is suitable for abroad range of substrates. The control experiments suggested a possible oxidative coupling mechanism.
Synthesis of α-ketoamides from Aryl methyl ketones and N, N -dimethylformamide via copper-catalyzed aerobic oxidative coupling
Zhou, Mingxin,Song, Qiuling
, p. 1853 - 1858 (2014/07/22)
A copper-catalyzed aerobic oxidative coupling of aryl methyl ketones with N,N-dimethylformamide was developed, which afforded α-ketoamides by a sequence of dioxygen activation, C-H bond functionalization, and amide formation with N,N-dimethylformamide as
