1629168-03-1Relevant articles and documents
Synthesis of chromane compounds and their derivatives by a copper-catalyzed conjugate addition reaction
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Paragraph 0198, (2015/05/06)
The present invention relates to the preparation of chromane compounds and their derivatives by a copper-catalyzed conjugate addition reaction. It has been observed that in highly stereoselective manner a methyl group can be introduced to the 2 position o
Total synthesis of (2RS)-α-tocopherol through Ni-catalyzed 1,4-addition to a chromenone intermediate
Termath, Andreas Ole,Velder, Janna,Stemmler, Rene T.,Netscher, Thomas,Bonrath, Werner,Schmalz, Hans-Guenther
supporting information, p. 3337 - 3340 (2014/06/09)
A novel strategy for the total synthesis of α-tocopherol ("vitamin E") was elaborated on the basis of the conjugate addition of AlMe3 (as a methyl anion equivalent) to a 2-substituted chromenone. Starting from trimethylhydroquinone and (R,R)-he