16308-16-0

Basic information

• Product Name: P-(DIACETOXYIODO)-TOLUENE
• Synonyms: P-(DIACETOXYIODO)-TOLUENE;AURORA KA-4364;4-Tolyliodine Diacetate;Zinc03957862;1-(Diacetoxyiodo)-4-methylbenzene;4-Tolyliodonium diacetate
• CAS NO: 16308-16-0
• Molecular Formula: C₁₁H₁₃IO₄
• Molecular Weight: 336.12
• Mol File: 16308-16-0.mol
• Article Data: 39

Chemical Properties

• Melting Point: 108-109℃
• Appearance: /
• CAS DataBase Reference: P-(DIACETOXYIODO)-TOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: P-(DIACETOXYIODO)-TOLUENE(16308-16-0)
• EPA Substance Registry System: P-(DIACETOXYIODO)-TOLUENE(16308-16-0)

Safety Data

• Hazardous Substances Data: 16308-16-0(Hazardous Substances Data)

Usage

General Description

P-(DIACETOXYIODO)-TOLUENE, also known as hypoiodous acid, is a chemical compound with the molecular formula C9H9IO4. It is a member of the family of iodoarenes, which are compounds containing a benzene ring with one or more iodine atoms attached. This specific compound is an iodoarene derivative, with the iodine atom attached to a para position on the benzene ring and acetoxy groups attached to it. P-(DIACETOXYIODO)-TOLUENE is an important reagent in organic synthesis, commonly used as an oxidizing agent in various reactions. It is also used as a reagent in the preparation of other iodine-containing organic compounds, and in the development of pharmaceuticals and agrochemicals. However, it is important to handle this compound with caution, as it is toxic and can cause skin and eye irritation.

Upstream product

• 624-31-7 4-tolyl iodide 
• 75-07-0 acetaldehyde 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 127-09-3 sodium acetate 
• 108-88-3 toluene 
• 19028-26-3 4-dichloroiodanyl-toluene 
• 546-67-8 lead(IV) tetraacetate 
• 79-21-0 peracetic acid 

Downstream Products

• 624-31-7 4-tolyl iodide 
• 64-19-7 acetic acid 
• 490-83-5 L-dehydroascorbic acid 
• 161564-34-7 1--4-methylbenzene 
• 53135-63-0 3-isopropoxyprop-1-yne 
• 131251-49-5 1-(2-iodo-5-methylphenyl)-2-propyne 
• 1382355-02-3 (2-(2-(t-butoxycarbonylamino)ethyl)phenyl)(p-tolyl)iodonium p-toluenesulfonate 
• 1382355-12-5 (2-(2-(benzyloxycarbonylamino)ethyl)phenyl)(p-tolyl)iodonium p-toluenesulfonate 
• 1382355-22-7 (2-(2-acetamidoethyl)phenyl)(p-tolyl)iodonium p-toluenesulfonate 
• 1382355-32-9 (2-(2-(3,3-diethylureido)ethyl)phenyl)(p-tolyl)iodonium p-toluenesulfonate 

Relevant articles and documents

Applications of hypervalent iodine(III) reagents in constructing ortho-iodo aromatic ethers

A one-pot method for the synthesis of aromatic ethers using hypervalent iodine(III) reagents obtained from the corresponding iodoaryl compounds is developed. In this concise method, six diaryl ethers and three heterocyclic aromatic ethers are synthesized in good yields. Furthermore, possible mechanisms for the syntheses of the hypervalent iodine reagents and construction of the aromatic ethers are proposed.

Photocatalytic Fluoro Sulfoximidations of Styrenes

Reactions of difluoroiodotoluene with NH-sulfoximines provide new hypervalent iodine(III) reagents, which photocatalytically transfer a fluoro and a sulfoximidoyl group onto styrenes with high regioselectivity. The substrate scope is broad with respect to

Method for producing hypervalent iodine compound

The invention provides a method for producing a hypervalent iodine compound; the method is more effective than the prior art, improves yield while reducing reaction time, and is more suitable for industrial application.