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1-[(4-[4-(6-fluoro-1,3-benzoxazol-2-yl)phenyl]carbonylpiperazin-1-yl)carbonyl]cyclopropan-1-ol is a complex organic compound characterized by the presence of a cyclopropane ring, a piperazine ring, and a benzoxazole moiety, all connected through a carbonyl group. Its intricate molecular structure, featuring multiple functional groups, suggests a wide range of potential pharmacological properties, making it a candidate for the development of new drugs to address various medical conditions. However, further research and testing are required to explore its specific applications and effects.

1630808-89-7

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1630808-89-7 Usage

Uses

Used in Pharmaceutical Industry:
1-[(4-[4-(6-fluoro-1,3-benzoxazol-2-yl)phenyl]carbonylpiperazin-1-yl)carbonyl]cyclopropan-1-ol is used as a potential drug candidate for the development of new medications due to its complex molecular structure and the presence of multiple functional groups that may exhibit a variety of pharmacological properties.
Used in Research and Development:
In the field of medicinal chemistry, 1-[(4-[4-(6-fluoro-1,3-benzoxazol-2-yl)phenyl]carbonylpiperazin-1-yl)carbonyl]cyclopropan-1-ol serves as a subject of research and development to understand its pharmacological properties, potential therapeutic effects, and possible side effects, which is essential for its application in drug discovery and development.

Check Digit Verification of cas no

The CAS Registry Mumber 1630808-89-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,3,0,8,0 and 8 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1630808-89:
(9*1)+(8*6)+(7*3)+(6*0)+(5*8)+(4*0)+(3*8)+(2*8)+(1*9)=167
167 % 10 = 7
So 1630808-89-7 is a valid CAS Registry Number.

1630808-89-7Downstream Products

1630808-89-7Relevant academic research and scientific papers

Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN)

Martin, Matthew W.,Lancia, David R.,Li, Hongbin,Schiller, Shawn E.R.,Toms, Angela V.,Wang, Zhongguo,Bair, Kenneth W.,Castro, Jennifer,Fessler, Shawn,Gotur, Deepali,Hubbs, Stephen E.,Kauffman, Goss S.,Kershaw, Mark,Luke, George P.,McKinnon, Crystal,Yao, Lili,Lu, Wei,Millan, David S.

, p. 1001 - 1006 (2019)

The discovery, structure-activity relationships, and optimization of a novel class of fatty acid synthase (FASN) inhibitors is reported. High throughput screening identified a series of substituted piperazines with structural features that enable interactions with many of the potency-driving regions of the FASN KR domain binding site. Derived from this series was FT113, a compound with potent biochemical and cellular activity, which translated into excellent activity in in vivo models.

NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN

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Page/Page column 245; 246; 331, (2014/10/18)

The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

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