163336-50-3

Basic information

• Product Name: Benzoic acid, 3-methoxy-2-methyl-, 2-(1,1-dimethylethyl)hydrazide
• CAS NO: 163336-50-3
• Molecular Formula: C13H20N2O2
• Molecular Weight: 236.314
• Mol File: 163336-50-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-methoxy-2-methyl-, 2-(1,1-dimethylethyl)hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-methoxy-2-methyl-, 2-(1,1-dimethylethyl)hydrazide(163336-50-3)
• EPA Substance Registry System: Benzoic acid, 3-methoxy-2-methyl-, 2-(1,1-dimethylethyl)hydrazide(163336-50-3)

Safety Data

• Hazardous Substances Data: 163336-50-3(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 3-methoxy-2-methyl-, 2-(1,1-dimethylethyl)hydrazide is a chemical compound used as a pesticide and herbicide. It acts as a growth regulator for various plants by inhibiting the production of gibberellins, a plant hormone that promotes growth. Benzoic acid, 3-methoxy-2-methyl-, 2-(1,1-dimethylethyl)hydrazide is also used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It has a molecular formula of C13H22N2O2 and a molecular weight of 234.32 g/mol. Its precise properties, such as physical appearance and specific applications, may vary depending on the specific formulation and use.

Upstream product

• 32064-67-8 tert-butylhydrazine 
• 55289-06-0 3-methoxy-2-methylbenzoic acid 
• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 42981-93-1 3-methoxy-2-methylbenzoic acid methyl ester 
• 118-69-4 2,6-dichlorotoluene 
• 24487-91-0 3-methoxy-2-methylbenzoyl chloride 
• 7400-27-3 tertbutylhydrazine hydrochloride 

Downstream Products

• 161050-58-4 methoxyfenoside 

Relevant articles and documents

Preparation method of 6-chloro-2-methoxytoluene and synthesis process of methoxyfenozide

The invention relates to the field of insecticides, in particular to a preparation method of 6-chloro-2-methoxytoluene and a synthesis process of methoxyfenozide. The preparation method of the 6-chloro-2-methoxytoluene comprises the following steps: in a solvent, mixing 2, 6-dichlorotoluene with sodium methoxide, and carrying out a substitution reaction to prepare a first reaction solution containing 3-chloro-2-sodium methylphenolate and the 6-chloro-2-methoxytoluene; and dropwise adding dimethyl sulfate into the first reaction solution, carrying out etherification reaction, removing 3-chloro-2-sodium methylphenolate to obtain a second reaction solution, and carrying out post-treatment to obtain the 6-chloro-2-methoxytoluene. The synthesis process of the methoxyfenozide comprises the following steps: preparing 3-methoxy-2-methyl benzoic acid by taking 6-chloro-2-methoxytoluene as an intermediate; using 3-methoxy-2-methyl benzoic acid and 3, 5-dimethyl benzoic acid as intermediates, and preparing to obtain the methoxyfenozide. According to the synthesis process disclosed by the invention, the yield and the purity of methoxyfenozide can be remarkably improved.

Synthesis and bioactivity of N-tert-butyl-N′-acyl-5-methyl-1,2,3- thiadiazole-4-carbohydrazides

A series of novel N-tert-butyl-N′-acyl-5-methyl-1,2,3-thiadiazole-4- carbohydrazides were designed and synthesized. Their structures were characterized by melting points, 1H NMR, IR, ESI-MS, and elemental analysis. The bioassay tests indicated that compound 7o exhibited excellent direct anti-TMV activity and induction activity in vivo at 50 μg/mL, which was better than that of Ninamycin and tiadinial. Our studies indicated that 1,2,3-thiadiazole was an active substructure for novel pesticide development.

Process for the preparation of 3-Alkoxy-2-methylbenzoic acids

Preparation of 3-alkoxy-2-methyl-benzoic acid compounds (I) involves: (a) reacting a naphthalene compound with alkali metal hydroxide in presence of water; (b) partially neutralizing; (c) treating with an alkyl halide, alkyl sulfonate or alkyl sulfate and (d) acidifying. Preparation of 3-alkoxy-2-methyl-benzoic acids of formula (I) involves: (a) reacting a naphthalene derivative of formula (III) with alkali metal hydroxide in presence of water; (b) partially neutralizing the reaction mixture (optionally after adding water, removing insolubles and/or removing undesirable soluble components); (c) reacting the mixture with an alkyl halide of formula R1X (IVa), an alkyl sulfonate of formula R1-OSO2-R8 (IVb) or a dialkyl sulfate of formula R1OSO2OR1 (IVc); and (d) acidifying the mixture. R1 = 1-14C alkyl, 7-20C aralkyl, 13-20C diarylalkyl, A-OR2 or A-NR3R4; A = 1-4C alkylene; R2, R3, R4 = Me, Et or isopropyl; R5-R7 = H, OH, NH2 or SO3M; M = H, ammonium, alkali metal or 1 equivalent of alkaline earth metal; X = Cl, Br or I, and R8 = 1-4C alkyl, 1-4C perfluoroalkyl, phenyl or p-tolyl.