16357-47-4

Upstream product

• 64-67-5 diethyl sulfate 
• 89-41-8 4-methoxy-3-nitrobenzoic acid 
• 67-56-1 methanol 
• 367-80-6 ethyl 4-fluoro-3-nitrobenzoate 
• 64-17-5 ethanol 

Downstream Products

• 16357-44-1 3-amino-4-methoxy-benzoic acid ethyl ester 
• 355425-79-5 4-hydrazino-3-nitro-benzoic acid ethyl ester 
• 1012071-56-5 ethyl 3-ethylamino-4-methoxybenzoate 
• 1042663-50-2 ethyl 3-benzylamino-4-methoxybenzoate 
• 400648-58-0 ethyl (3-amino-4-methoxyphenyl)acetate 
• 89-41-8 4-methoxy-3-nitrobenzoic acid 

Relevant academic research and scientific papers

Benzimidazole ring-containing propyne amide derivative as well as preparation method and pharmaceutical composition and application thereof

The invention relates to a benzimidazole ring-containing propiolamide derivative as shown in the formula I, its medicinal salt and their preparation method, a composition containing one or more of the compounds and an application of the compounds in treating tumor diseases.

Synthesis of symmetric diester-functionalised Troeger's base analogues

The yields of ester-functionalised Troeger's base analogues are dramatically improved by incorporating an electron-donating group on the aromatic ring and/or enhancing solubil- ity of the aniline unit. In addition to 2,8-diester compounds, 1,7-, 3,9- and 4,10-diester-functionalised Troeger's base analogues have been prepared for the first time.