16358-71-7Relevant academic research and scientific papers
Large-steric hindrance chiral quaternary ammonium salt phase transfer catalyst derived from cinchona alkaloid and synthesis method thereof
-
Paragraph 0054-0058, (2021/10/27)
The invention discloses a large-steric hindrance chiral quaternary ammonium salt phase transfer catalyst derived from cinchona alkaloid. The invention belongs to the technical field of asymmetric catalysis. In the invention, the cinchona alkaloid is disso
Atropisomerism in Diarylamines: Structural Requirements and Mechanisms of Conformational Interconversion
Clayden, Jonathan,Costil, Romain,Duarte, Fernanda,Sterling, Alistair J.
supporting information, p. 18670 - 18678 (2020/08/25)
In common with other hindered structures containing two aromatic rings linked by a short tether, diarylamines may exhibit atropisomerism (chirality due to restricted rotation). Previous examples have principally been tertiary amines, especially those with
Catalytic Asymmetric Hydroalkenylation of Vinylarenes: Electronic Effects of Substrates and Chiral N-Heterocyclic Carbene Ligands
Ho, Chun-Yu,Chan, Chun-Wa,He, Lisi
supporting information, p. 4512 - 4516 (2015/04/14)
An asymmetric tail-to-tail cross-hydroalkenylation of vinylarenes with terminal olefins was achieved by catalysis with NiH complexes bearing chiral N-heterocyclic carbenes (NHCs). The reaction provides branched gem-disubstituted olefins with high enantioselectivity (up to 94% ee) and chemoselectivity (cross/homo product ratio: up to 99:1). Electronic effects of the substituents on the vinylarenes and on the N-aryl groups of the NHC ligands, but not a π,π-stacking mechanism, assist the steric effect and influence the outcome of the cross-hydroalkenylation.
Catalytic enantioselective alkylation of sulfenate anions to chiral heterocyclic sulfoxides using halogenated pentanidium salts
Zong, Lili,Ban, Xu,Kee, Choon Wee,Tan, Choon-Hong
supporting information, p. 11849 - 11853 (2015/02/19)
We report halogenated pentanidiums as phasetransfer catalysts for the asymmetric alkylation of sulfenate anions to various sulfoxides with high enantio selectivities (up to 99% ee) and yields (up to 99%). This approach gives access to enantioenriched heterocyclic sulfoxides that might not be compatible with strong oxidants or organometallic reagents. Computational studies have revealed that the multiple non-covalent interactions such as halogen bonds and nonclassical hydrogen bonds are involved.
Enantioselective copper-catalyzed 1,4-addition of dialkylzincs to enones followed by trapping with allyl iodide derivatives
Kawamura, Kenjiro,Fukuzawa, Hitomi,Hayashi, Masahiko
supporting information; experimental part, p. 640 - 647 (2011/08/06)
Enantioselective copper-catalyzed 1,4-addition of dialkylzincs to enones proceeded in the presence of 0.1 mol% of Cu(OTf)2 and 0.25 mol% of an N,N,P-ligand containing a quinoline moiety to afford the corresponding conjugated adducts in 99%ee. The intermediate zinc enolates were trapped with substituted allyl iodides to give disubstituted ketones with high diastereoselectivity and enantioselectivity.
Synthesis of 2,2c-6-trisubstituted and 2,2c-,6,6--tetrasubstituted diaryl sulfides and diaryl sulfones by copper-promoted coupling and/or ortholithiation
Clayden, Jonathan,Senior, James
scheme or table, p. 2769 - 2772 (2010/02/28)
Stoichiometric copper(I) iodide, in the presence of potassium carbonate and ethylene glycol, promotes the coupling of even highly sterically encumbered 2,6-disubstituted thiophenols and aryl iodides to form hindered diarylsulfides. Hindered diarylsulfones
Phenylthiyl radical complexes of gallium(III), iron(III), and cobalt(III) and comparison with their phenoxyl analogues
Kimura,Bill,Bothe,Weyhermueller,Wieghardt
, p. 6025 - 6039 (2007/10/03)
Three hexadentate, asymmetric pendent arm macrocycles containing a 1,4,7-triazacyclononane-1,4-diacetate backbone and a third, N-bound phenolate or thiophenolate arm have been synthesized. In [L1]3- the third arm is 3,5-di-tert-butyl
Formation of Persistent Benzyl Radicals by Protonation of the Radical Anions of Sterically Hindered Dithiobenzoic Esters
Edler, Ronald,Voss, Juergen
, p. 187 - 192 (2007/10/02)
ESR signals due to a second species are observed besides the spectra of the corresponding radical anions when the methyl ortho-(tert-butyl)dithiobenzoates 1, 4, and 6 are electroreduced in situ in dimethylformamide.It is shown by investigation of model co
Contributions to the Chemistry of Phosphorus,184. - Existence and Properties of a Phosphinidenediphosphirane (R1P)2C=PR2
Baudler, Marianne,Simon, Joachim
, p. 281 - 286 (2007/10/02)
The reaction of K(tBu)P-P(tBu)K with the (dichloromethylene)phosphane 2,4-tBu2-6-MeC6H2P=CCl2 (1) yields the first phosphinidenediphosphirane (tBuP)2C=P-(2,4-tBu2-6-Me-C6H2) (2).Further products are the cyclophosphanes (tBuP)n (n=3,4) as well as the phosp
