1637593-17-9Relevant academic research and scientific papers
A new and practical synthesis of 7-(3-chloropropoxy)-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile
Mao, Yongjun,Qin, Jianfeng,He, Haijun,Liu, Gang,Gao, Bingyi,Wang, Han
, p. 1885 - 1891 (2014/08/18)
New and improved synthetic route of bosutinib intermediate 7-(3-chloropropoxy)-6-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonitrile (3) is described on a hectogram scale. An intramolecular cyclization of 3-(2-aminophenyl)-3-oxopropanenitrile 11 with DMF-DM
