1639866-72-0

Basic information

• Product Name: 3-amino-5-ethynylbenzoic acid
• Synonyms: 3-amino-5-ethynylbenzoic acid
• CAS NO: 1639866-72-0
• Molecular Weight: 161.16
• Mol File: 1639866-72-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-amino-5-ethynylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-5-ethynylbenzoic acid(1639866-72-0)
• EPA Substance Registry System: 3-amino-5-ethynylbenzoic acid(1639866-72-0)

Safety Data

• Hazardous Substances Data: 1639866-72-0(Hazardous Substances Data)

Usage

General Description

3-amino-5-ethynylbenzoic acid is a chemical compound with the molecular formula C9H7NO2. It is a derivative of benzoic acid and contains an amino group and an ethynyl group on the benzene ring. 3-amino-5-ethynylbenzoic acid is used in organic synthesis and pharmaceutical research, particularly in the development of new drugs and medicines. It has potential applications in the fields of medicinal chemistry, biochemistry, and pharmacology due to its unique chemical structure and properties. 3-amino-5-ethynylbenzoic acid has also been studied for its potential anti-cancer and anti-inflammatory properties, making it a promising candidate for further biomedical research and development.

Upstream product

• 1639866-71-9 3-ethynyl-5-nitrobenzoic acid 
• 50765-19-0 methyl 3-iodo-5-nitrobenzoate 
• 23218-93-1 3-amino-5-nitro-benzoic acid methyl ester 
• 99-34-3 3,5-dinitrobenzoic acid 
• 6307-87-5 methyl 3-bromo-5-nitrobenzoate 
• 6307-83-1 3-bromo-5-nitro-benzoic acid 

Relevant articles and documents

POLYIMIDE-POLYARYLENE POLYMERS

Disclosed is a bis-imide compound comprising two or more aryl moieties substituted with ethynyl moieties and the two or more aryl moieties each having one or more polar substituents. Further disclosed is a polymer composition comprising a copolymer polymerized from a monomer mixture of (a) one or more first monomers comprising a bis-imide compound comprising two or more aryl moieties substituted with ethynyl moieties and the two or more aryl moieties each having one or more polar substituents; and (b) one or more second monomers comprising two or more cyclopentadienone moieties. The polymer compositions exhibit favorable properties for use in electronics and displays applications.

Preparation of new alkyne-modified ansamitocins by mutasynthesis

The preparation of alkyne-modified ansamitocins by mutasynthetic supplementation of Actinosynnema pretiosum mutants with alkyne-substituted aminobenzoic acids is described. This modification paved the way to introduce a thiol linker by Huisgen-type cycloaddition which can principally be utilized to create tumor targeting conjugates. In bioactivity tests, only those new ansamitocin derivatives showed strong antiproliferative activity that bear an ester side chain at C-3.