1639866-72-0

Usage

Uses

Used in Pharmaceutical Research:
3-amino-5-ethynylbenzoic acid is used as a key intermediate in organic synthesis for the development of new drugs and medicines. Its unique chemical structure allows for the creation of novel compounds with potential therapeutic effects.
Used in Medicinal Chemistry:
3-amino-5-ethynylbenzoic acid is utilized as a building block in the design and synthesis of pharmaceutical agents, contributing to the advancement of drug discovery and development.
Used in Biochemistry:
3-amino-5-ethynylbenzoic acid serves as a valuable tool in biochemical research, aiding in the study of enzyme mechanisms, protein interactions, and other biological processes.
Used in Pharmacology:
3-amino-5-ethynylbenzoic acid is employed in pharmacological research to investigate its potential anti-cancer and anti-inflammatory properties, contributing to the development of new therapeutic agents for the treatment of various diseases.
Used in Biomedical Research and Development:
3-amino-5-ethynylbenzoic acid is explored for its potential applications in the biomedical field, with ongoing studies focusing on its ability to target specific biological pathways and develop new treatment strategies for various medical conditions.

Upstream product

• 1639866-71-9 3-ethynyl-5-nitrobenzoic acid 
• 50765-19-0 methyl 3-iodo-5-nitrobenzoate 
• 23218-93-1 3-amino-5-nitro-benzoic acid methyl ester 
• 99-34-3 3,5-dinitrobenzoic acid 
• 6307-87-5 methyl 3-bromo-5-nitrobenzoate 
• 6307-83-1 3-bromo-5-nitro-benzoic acid 

Relevant academic research and scientific papers

POLYIMIDE-POLYARYLENE POLYMERS

Disclosed is a bis-imide compound comprising two or more aryl moieties substituted with ethynyl moieties and the two or more aryl moieties each having one or more polar substituents. Further disclosed is a polymer composition comprising a copolymer polymerized from a monomer mixture of (a) one or more first monomers comprising a bis-imide compound comprising two or more aryl moieties substituted with ethynyl moieties and the two or more aryl moieties each having one or more polar substituents; and (b) one or more second monomers comprising two or more cyclopentadienone moieties. The polymer compositions exhibit favorable properties for use in electronics and displays applications.

Design of photoaffinity labeling probes derived from 3,4,5-trimethylfuran-2(5H)-one for mode of action elucidation

Herein we report the synthesis of new probes for photoaffinity labeling with the aim of receptor identification and mode of action elucidation of 3,4,5-trimethylfuran-2(5H)-one (TMB), recently identified in the smoke of burning vegetation as an efficient seed germination inhibitor. These photoaffinity probes consist of an ethynyl group that acts as a tag for introduction of an optional detectable marker unit by an appropriate chemoselective ligation method after the photo-cross-linking operation.

Preparation of new alkyne-modified ansamitocins by mutasynthesis

The preparation of alkyne-modified ansamitocins by mutasynthetic supplementation of Actinosynnema pretiosum mutants with alkyne-substituted aminobenzoic acids is described. This modification paved the way to introduce a thiol linker by Huisgen-type cycloaddition which can principally be utilized to create tumor targeting conjugates. In bioactivity tests, only those new ansamitocin derivatives showed strong antiproliferative activity that bear an ester side chain at C-3.