1640-44-4

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 619-56-7 4-chlorobenzamide 
• 551-93-9 2-aminoacetophenone 
• 122-01-0 4-chloro-benzoyl chloride 
• 79498-43-4 2-(4-Chloro-phenyl)-3-methyl-3H-indol-3-yl-hydroperoxide 

Downstream Products

• 78396-10-8 2-(4’-chlorophenyl)-4-quinolone 
• 1643-59-0 2-(4-chlorophenyl)-4-methylquinazoline 3-oxide 
• 1640-50-2 N-(p-Chlorbenzoyl)-2-aminoacetophenonoxim 
• 106657-37-8 N-methyl-2-(p-chlorophenyl)-quinolin-4(1H)-one 

Relevant academic research and scientific papers

E-N-(2-acetyl-phenyl)-3-phenyl-acrylamide targets abrin and ricin toxicity: Hitting two toxins with one stone

The efficacy of small molecule inhibitors (SMIs) against the enzymatic activity of Shiga toxin prompted the evaluation of their efficacy on related toxins viz. ricin and abrin. Ricin, like Shiga toxin, is listed as a category B bioweapon and belongs to th

Mild, rapid and efficient metal-free synthesis of 2-aryl-4-aryloxyquinolines via direct Csp2[sbnd]O bond formation by using diaryliodonium salts

An efficient ligand- and transition metal-free procedure for the direct Csp2[sbnd]O bond formation for the arylation of 2-aryl-4-quinolones was developed. The synthesis of the starting quinolones was carried out under our optimized C

Copper-mediated selective C-H activation and cross-dehydrogenative C-N coupling of 2′-aminoacetophenones

Isatins were obtained by cross-dehydrogenative C-N annulation and dealkylative C-N annulation of 2′-N-aryl/alkylaminoacetophenones and 2′-N,N-dialkylaminoacetophenones respectively in the presence of Cu(OAc)2·H2O/NaOAc/air. However, on reaction with CuBr, 2′-N-benzylaminoacetophenones underwent selective oxidation of an α-methylene group of amine rather than the 2-acetyl group to provide corresponding benzamides exclusively. Base played an important role in selective oxidation by lowering the temperature and time.

Tautomeric 2-arylquinolin-4(1H)-one derivatives- spectroscopic, X-ray and quantum chemical structural studies

A convenient method for the synthesis of 2-aryl-1-methylquinolin-4(1H) -ones is described. Spectroscopic and X-ray crystallographic techniques as well as quantum chemical calculations have been used to probe the structure of potentially tautomeric 2-arylq

THE REARRANGEMENT OF HYDROPEROXYINDOLENINES

Examination of a series of substituted 3-(hydroxyperoxy)indolenines favours a mechanism for base catalysed decomposition of the dioxetan rather than Criegee type.