16408-78-9

Usage

InChI:InChI=1/C19H13NO5/c1-22-12-6-10-11(7-13(12)23-2)18(21)17-15-9(3-4-20-17)5-14-19(16(10)15)25-8-24-14/h3-7H,8H2,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 87264-30-0 machigline 
• 80041-86-7 C₂₁H₁₇NO₅ 
• 26110-43-0 dicentrine 
• 73357-18-3 (4,5-dimethoxy-2-nitrophenyl)acetic acid 
• 53602-52-1 4,5-dimethoxy-2-nitrophenylacetic acid chloride 
• 80041-83-4 1-(2-Bromo-4,5-dimethoxy-phenyl)-4,5-dihydro-7,9-dioxa-3a-aza-dicyclopenta[a,g]naphthalene-2,3-dione 
• 80041-80-1 5-(2-bromo-4,5-dimethoxy-benzyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline 
• 25394-59-6 nordicentrine 

Related news

Antioxidant, anti-rheumatic and anti-inflammatory investigation of extract and dicentrinone (cas 16408-78-9) from Duguetia furfuracea (A. St.-Hil.) Benth. & Hook. f.08/05/2019

Ethnopharmacological relevanceThe preparations of teas and syrups using Duguetia furfuracea have been used in folk medicine to treat rheumatism and back pain. Several rheumatic diseases are anti-inflammatory and are treated with several anti-inflammatories.detailed

Relevant academic research and scientific papers

ALKALOIDS OF LITSAEA LAETA AND L. SALICIFOLIA

The structure for laetine (2-hydroxy-1-methyl 10,11-methylenedioxy noraporphine), a new alkaloid from the bark of Litsaea laeta has been established.N,O-Dimethylharnovine and glaucine were also isolated from the same source.C-2 hydroxy aporphines are characteristic of L. laeta.Two known alkaloids, dicentrinone and nordicentrine, have also been isolated from the leaves of L. salicifolia. - Key Word Index: Litsaea laeta; L. salicifolia; Lauraceae; new noraporphine alkaloid; structure determination.

Synthesizing method of oxidized dicentrine

The invention discloses a synthesizing method of oxidized dicentrine. The synthesizing method comprises the following steps of using 3,4-dimethoxyphenylacetic acid as the start raw material, reactingwith bromine to obtain a product, and then reacting with

Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs

Novel total syntheses of oxoaporphine alkaloids such as liriodenine, dicentrinone, cassameridine, lysicamine, oxoglaucine and O-methylmoschatoline were developed. The key step of these total syntheses is Cu-catalyzed conversion of 1-benzyl-3,4-dihydro-isoquinolines (1-Bn-DHIQs) to 1-benzoyl-isoquinolines (1-Bz-IQs) via tandem oxidation/aromatization. This novel Cu-catalyzed conversion has been studied in detail, and was successfully used for constructing the 1-Bz-IQ core.

Alkaloids of Machilus glaucescens Wight: Machigline, A New Phenolic Oxoaporphine Alkaloid

Machigline (I), a new phenolic oxoaporphine alkaloid, isolated along with atheroline (II) and β-sitosterol-O-β-D-glucoside from the alcohol extract of the leaves of Machilus glaucescens Wight (Lauraceae), has been shown to be 1,2-methylenedioxy-9-hydroxy-10-methoxyoxoaporphine by spectral and chemical studies.A fatty ketol characterised as a rarely occurring n-hentriacotan-10-ol-16-one (10-hydroxypalmitone) (III); (first report of its occurrence in Lauraceae) has also been isolated as an aliphatic constituent from the CHCl3 extract of the plant besides the lignan and nor-lignan constituents.The mass fragmentation of I and III have been delinated.The isolation of machigline and atheroline constitutes the firsent report on the occurrence of oxoaporphines in Machilus species, and machigline adds a new name to the list of only a few phenolic oxoaporphines.

FREMY'S SALT OXIDATION OF SOME ISOQUINOLINE ALKALOIDS. BIOGENETIC CONSIDERATIONS

Fremy's salt oxidation of benzylisoquinoline and aporphine alkaloids to isoquinolones and oxoaporphines is described.Aminium radicals are suggested to account for the observed results.Their possible involvement in alkaloid biosynthesis is considered.