53602-52-1

Basic information

• Product Name: 4,5-dimethoxy-2-nitrophenylacetic acid chloride
• Synonyms: 4,5-dimethoxy-2-nitrophenylacetic acid chloride
• CAS NO: 53602-52-1
• Molecular Weight: 259.646
• Mol File: 53602-52-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,5-dimethoxy-2-nitrophenylacetic acid chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-dimethoxy-2-nitrophenylacetic acid chloride(53602-52-1)
• EPA Substance Registry System: 4,5-dimethoxy-2-nitrophenylacetic acid chloride(53602-52-1)

Safety Data

• Hazardous Substances Data: 53602-52-1(Hazardous Substances Data)

Upstream product

• 73357-18-3 (4,5-dimethoxy-2-nitrophenyl)acetic acid 

Downstream Products

• 79831-93-9 4,5-dimethoxy-2-nitro-N-(3,4,5-trimethoxyphenethyl)phenylacetamide 
• 20323-72-2 (6,7-dimethoxyisoquinolin-1-yl)(4,5-dimethoxy-2-nitrophenyl)-methanone 
• 16408-78-9 dicentrinone 
• 2129-52-4 N-(3,4-dimethoxyphenethyl)-2-(4,5-dimethoxy-2-nitrophenyl)-acetamide 
• 16251-41-5 1-(2'-nitro-4',5'-dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline 
• 79832-06-7 1-(4,5-dimethoxy-2-nitrobenzyl)-1,2,3,4-tetrahydro-6,7,8-trimethoxy-2-methylisoquinoline 
• 79832-10-3 1-(4,5-dimethoxy-2-nitrobenzyl)-3,4-dihydro-6,7,8-trimethoxyisoquinoline 
• 79832-04-5 4,5-Dimethoxy-2-(6,7,8-trimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-phenylamine 
• 79832-27-2 1-(4,5-dimethoxy-2-nitrobenzyl)-3,4-dihydro-6,7,8-trimethoxyisoquinoline methiodide 
• 549-28-0 protostephanine 
• 20824-18-4 protostephanone 

Relevant articles and documents

Synthesis along Biosynthetic Pathways. Part 2. Synthesis of Protostephanine

The dienone protostephanone (3) is synthesised by phenol coupling or by Pschorr cyclisation from readily prepared tetrahydroisoquinolines, and the corresponding dienols (17) and (18) are converted by rearrangement, fragmentation, and reduction into protostephanine (4).This sequence mimics the natural pathway to the alkaloid.