164208-54-2

Upstream product

• 22056-04-8 2-[(4-chlorophenyl)hydroxymethyl]acrylonitrile 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 1020666-76-5 ethyl 2-acetyl-3-(4-chlorophenyl)-4-cyanopent-4-enoate 
• 1020667-35-9 ethyl 1-[1-(4-chlorophenyl)-2-cyanoallyl]-2-oxocyclopentanecarboxylate 
• 1020666-66-3 2-[2-acetyl-1-(4-chlorophenyl)-3-oxobutyl]acrylonitrile 
• 1072836-69-1 C₁₈H₁₂ClN 
• 1072836-53-3 C₁₈H₁₂ClN 
• 1072513-46-2 3-(4-chlorophenyl)-2-{[(2,2-dimethoxyethyl)amino]methyl}prop-2-enenitrile 
• 1134780-64-5 C₁₆H₁₇ClN₂S₂ 
• 1134780-66-7 C₁₅H₁₇ClN₂S₂ 
• 1134780-68-9 C₁₈H₁₅ClN₂S₂ 
• 1186205-37-7 ethyl (Z)-5-(4-chlorophenyl)-4-cyano-2-nitropent-4-enoate 
• 1224508-59-1 ethyl 6-amino-5-(4-chlorobenzyl)-2-methylnicotinate 
• 1224508-65-9 methyl 6-amino-5-(4-chlorobenzyl)-2-methylnicotinate 
• 594835-24-2 (2E)-3-(4-chlorophenyl)-2-{[(4-methylphenyl)sulfonyl]methyl}prop-2-enenitrile 

Relevant academic research and scientific papers

A one-pot three-step multicomponent synthesis of functionalized allyl dithiocarbamates using Baylis–Hillman reaction

A one-pot, pseudo five-component, highly diastereoselective, and mild procedure for the synthesis of functionalized allyl dithiocarbamates is developed. The Baylis–Hillman (BH) reaction of aromatic (heteroaromatic) aldehydes and activated alkenes using DA

N-bromosuccinimide-mediated radical cyclization of 3-arylallyl azides: Synthesis of 3-substituted quinolines

Visible light irradiation of N-bromosuccinimide serves as an effective means to convert methyl 2-(azidomethyl)-3-arylpropenoates and 2-(azidomethyl)-3-arylacrylonitriles to the corresponding iminyl radicals via ?±-hydrogen abstraction and subsequent extrusion of dinitrogen. Thus formed iminyl radicals then undergo intramolecular ortho attack on the aryl ring, affording methyl quin-oline-3-carboxylates and quinoline-3-carbonitriles respectively.

Synthesis of allyl aryl sulfone derivatives from Baylis-Hillman acetates in water

Various phenyl and p-tolyl allyl sulfone derivatives were prepared stereoselectively by reacting Baylis-Hillman acetates with sodium 4-R-benzenesulfinate (R=H, Me) in H2O. The reaction was very efficient in providing the corresponding sulfone d

Synthesis of substituted 3-methylene-2-pyridones from Baylis-Hillman derivatives and its application for the generation of 2-pyridone substituted spiroisoxazolines

The synthesis of substituted 3-methylene-2-pyridones via SN2 displacement reaction of nucleophiles bearing a keto group on the acetyl derivative of Baylis-Hillman adducts of acrylonitrile followed by TFA/H2SO4-mediated int