16423-51-1

Basic information

• Product Name: N,N-DI-N-HEXYLACETAMIDE
• Synonyms: N,N-DI-N-HEXYLACETAMIDE;N,N-Di-n-hexylacetamide, 98+%;N,N-DIHEXYLACETAMIDE
• CAS NO: 16423-51-1
• Molecular Formula: C₁₄H₂₉NO
• Molecular Weight: 227.39
• EINECS: -0
• Mol File: 16423-51-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 130°C 2mm
• Flash Point: 130°C/2mm
• Appearance: /
• Density: 0.86
• Vapor Pressure: 0.00289mmHg at 25°C
• Refractive Index: 1.4490
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 1772656
• CAS DataBase Reference: N,N-DI-N-HEXYLACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DI-N-HEXYLACETAMIDE(16423-51-1)
• EPA Substance Registry System: N,N-DI-N-HEXYLACETAMIDE(16423-51-1)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 16423-51-1(Hazardous Substances Data)

Usage

Description

N,N-DI-N-HEXYLACETAMIDE is a colorless liquid chemical compound derived from acetamide, featuring two hexyl groups as alkyl chains. It is characterized by its faint odor and insolubility in water, while being soluble in many organic solvents. N,N-DI-N-HEXYLACETAMIDE is known for its versatile applications across different industries due to its unique properties.

Uses

Used in Chemical Industry:
N,N-DI-N-HEXYLACETAMIDE is used as a solvent for various polymers, resins, and other organic compounds, leveraging its solubility in organic solvents and its ability to dissolve a wide range of substances.
Used as a Lubricant Additive:
In the lubricant industry, N,N-DI-N-HEXYLACETAMIDE is utilized as a lubricant additive to enhance the performance and efficiency of lubricating oils, thanks to its compatibility with organic materials.
Used in Pharmaceutical Production:
N,N-DI-N-HEXYLACETAMIDE plays a role in the manufacturing of pharmaceuticals, where its solubility and chemical properties are beneficial for the formulation and processing of medications.
Used in Personal Care Products:
N,N-DI-N-HEXYLACETAMIDE is incorporated into the production of personal care products such as lotions, creams, and hair care products, contributing to their texture, consistency, and effectiveness.
Despite its wide range of applications, it is important to handle N,N-DI-N-HEXYLACETAMIDE with care due to its potential to cause irritation to the skin, eyes, and respiratory system if not properly managed.

InChI:InChI=1/C14H29NO/c1-4-6-8-10-12-15(14(3)16)13-11-9-7-5-2/h4-13H2,1-3H3

Upstream product

• 2466-76-4 N-Acetylimidazole 
• 143-16-8 dihexylamine 
• 75-36-5 acetyl chloride 
• 89583-95-9 Hexylmagnesiumiodid 
• 108-24-7 acetic anhydride 

Downstream Products

• 21983-64-2 N-nitrodihexylamine 

Relevant articles and documents

Preparation of mixed carbamic/dithiocarbamic anhydrides via silyl carbamates or silyl dithiocarbamates

The reactions of silyl carbamates and silyl dithiocarbamates with different acid chlorides (carbamoyl/thiocarbamoyl chloride, chloroformates, etc.) have been studied. The obtained mixed anhydrides have different thermal stability. Copyright Taylor & Francis Group, LLC.

Using dialkyl amide: Via forming hydrophobic deep eutectic solvents to separate citric acid from fermentation broth

Nowadays, developing appropriate technology is one of the biggest challenges for society to reduce environmental impact. In this research, to avoid the traditional calcium salt method which produces a large amount of waste gypsum residue, a new way of separating citric acid from fermentation broth was developed by forming hydrophobic deep eutectic solvents (DESs), in which amide and citric acid were used as the hydrogen bond acceptor and donor respectively when amide was in contact with the fermentation broth containing citric acid. Among these amides, C10H21NO was found to be an efficient hydrogen bond acceptor forming hydrophobic DESs with the citric acid based on the molecular size and shape and has the largest hydrophobic equilibrium constant of 3.14. The hydrophobic DES formation mechanism was studied by analyzing the chemical bonds using FT-IR and quantum chemical (QC) calculations. C10H21NO was regenerated by elevating the temperature of the hydrophobic DESs. The regenerated C10H21NO exhibited good recycling properties with no obvious reduction of the ability to form hydrophobic DESs. This effective way of obtaining high-quality citric acids provides new ideas for the separation of other carboxylic acids.

Nucleophilic Attack at Heterocyclic Nitrogen: Unusual Reactivity of the Benzotriazole Heterocyclic Ring

Grignard reagents attack 1-imidoylbenzotriazoles at the imidoyl carbon atom and also at the benzotriazolyl N-2 and N-3 atoms leading to complex reaction mixtures, the composition of which allowed identification of the main reaction paths.Mechanisms are discussed.Previous examples of nucleophilic attack on pyridine-like nitrogen atoms are reviewed.The 1-imidoylbenzotriazoles were prepared from amides with benzotriazole and phosphoryl chloride.Amides derived from secondary amines give α-(benzotriazol-1-yl)enamines.