16452-51-0

Basic information

• Product Name: Hexadecanoic acid, 2-hydroxy-, (2R)-
• Synonyms: (R)-2-Hydroxy-hexadecansaeure;2R-hydroxyhexadecanoic acid;Lanopalminsaeure;2R-hydroxypalmitic acid;(2R)-2-hydroxyhexadecanoic acid;D-2-Hydroxy-palmitinsaeure;Hexadecanoic acid,2-hydroxy-,(2R);(R)-2-hydroxyhexadecanoic acid;(R)-2OH PA
• CAS NO: 16452-51-0
• Molecular Formula: C16H32O3
• Molecular Weight: 272.428
• Mol File: 16452-51-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Hexadecanoic acid, 2-hydroxy-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexadecanoic acid, 2-hydroxy-, (2R)-(16452-51-0)
• EPA Substance Registry System: Hexadecanoic acid, 2-hydroxy-, (2R)-(16452-51-0)

Safety Data

• Hazardous Substances Data: 16452-51-0(Hazardous Substances Data)

Upstream product

• 98393-19-2 (R)-2-aminohexadecanoic acid 
• 57-10-3 1-hexadecylcarboxylic acid 
• 98393-18-1 D-2-chloroacetamidohexadecanoic acid 
• 7769-79-1 2-aminohexadecanoic acid 
• 112-71-0 1-Bromotetradecane 
• 16742-51-1 methyl 2-hydroxypalmitate 
• 112-39-0 hexadecanoic acid methyl ester 
• 764-67-0 2-hydroxypalmitic acid 
• 88642-46-0 1-O-(β-D-glucopyranosyl)-(2S,3R,4E,8E)-2-[(2'R)-2'-(hydroxyhexadecanoyl)amido]-9-methyl-4,8-octadecadiene-1,3-diol 
• 154857-69-9 (R)-2-((S)-2-Acetoxy-2-phenyl-acetoxy)-hexadecanoic acid methyl ester 
• 16742-51-1 methyl (R)-2-hydroxyhexadecanoate 
• 108-05-4 vinyl acetate 

Downstream Products

• 16742-51-1 methyl (R)-2-hydroxyhexadecanoate 
• 78330-57-1 (2S)-2-hydroxyhexadecanoic acid methyl ester 
• 115074-93-6 soya-cerebroside II 
• 88195-82-8 p-nitrophenyl 2-O-acetyl-(2R)-2-hydroxypalmitate 
• 16452-52-1 (S)-2-hydroxyhexadecanoic acid 
• 115523-77-8 Acetic acid (R)-1-((3E,7Z)-(1S,2R)-2-hydroxy-1-trityloxymethyl-heptadeca-3,7-dienylcarbamoyl)-pentadecyl ester 
• 115589-64-5 Acetic acid (R)-1-((3E,7Z)-(1R,2S)-2-hydroxy-1-trityloxymethyl-heptadeca-3,7-dienylcarbamoyl)-pentadecyl ester 
• 115648-52-7 Benzoic acid (2E,6Z)-(S)-1-[(R)-1-((R)-2-acetoxy-hexadecanoylamino)-2-hydroxy-ethyl]-hexadeca-2,6-dienyl ester 
• 115538-45-9 Benzoic acid (2E,6Z)-(R)-1-[(S)-1-((R)-2-acetoxy-hexadecanoylamino)-2-hydroxy-ethyl]-hexadeca-2,6-dienyl ester 
• 100924-06-9 (4E,8E,2S,3R,2'R)-N-2'-hydroxyhexadecanoyl-3-O-(t-butyldiphenylsilyl)-9-methyl-4,8-sphingadienine 
• 100924-05-8 (4E,8E,2S,3R,2'R)-N-2'-acetoxyhexadecanoyl-1-O-benzoyl-3-O-(t-butyldiphenylsilyl)-9-methyl-4,8-sphingadienine 
• 100924-07-0 (4E,8E,2S,3R,2'R)-N-2'-hydroxyhexadecanoyl-1-O-β-D-glucopyranosyl-3-O-(t-butyldiphenylsilyl)-9-methyl-4,8-sphingadienine 
• 100933-63-9 (4E,8E,2S,3R,2'R)-N-2'-hydroxyhexadecanoyl-1-O-(tetra-O-acetyl-β-D-glucopyranosyl)-3-O-(t-butyldiphenylsilyl)-9-methyl-4,8-sphingadienine 
• 88642-46-0 1-O-(β-D-glucopyranosyl)-(2S,3R,4E,8E)-2-[(2'R)-2'-(hydroxyhexadecanoyl)amido]-9-methyl-4,8-octadecadiene-1,3-diol 

Relevant articles and documents

Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy

(Chemical Equation Presented) In this paper, a new synthetic route toward 6-hydroxysphingosine and α-hydroxy ceramide is described. The synthesis employs a cross-metathesis to unite a sphingosine head allylic alcohol with a long-chain fatty acid alkene that also bears an allylic alcohol group. To allow for a productive CM coupling, the sphingosine head allylic alcohol was protected with a cyclic carbonate moiety and a reactive CM catalyst system, consisting of Grubbs II catalyst and CuI, was employed.

Enantioselective α-hydroperoxylation of long-chain fatty acids with crude enzyme of marine green alga Ulva pertusa

When palmitic acid was incubated with crude enzyme of marine green alga Ulva pertusa, (R)-2-hydroperoxyhexadecanoic acid was formed in high enantiomeric purity (>99%ee).

Enantioselective α hydroxylation of carboxylic acids with molecular oxygen catalyzed by the α oxidation enzyme system of young pea leaves (Pisum sativum): A substrate selectivity study

The substrate selectivity of the α oxidation of carboxylic acids 1 by crude homogenate of young pea leaves was investigated. Saturated fatty acids with 7 to 16 carbon atoms and oleic acid were transformed to the enantiomerically pure (R)-2-hydroxy acids 2 in the presence of molecular oxygen.