16452-52-1Relevant academic research and scientific papers
ENZYMATIC FORMATION OF (2R)-HYDROXY- AND 2-OXO-HEXADECANOIC ACID IN ULVA PERTUSA AND PORPHYRA SP.
Kajiwara, Tadahiko,Kashibe, Masanori,Matsui, Kenji,Hatanaka, Akikazu
, p. 193 - 195 (1991)
(2R)-Hydroxy-hexadecanoic acid and 2-oxo-hexadecanoic acid have been isolated for the first time from marine algae (Ulva pertusa and Porphyra sp.).The two acids were shown to be formed enzymatically from palmitic acid (16:0) using palmitic acid.
Spicamycin derivatives and their use as anticancer agents
-
, (2008/06/13)
Spicamycin derivative represented by the formula (I) or a salt thereof: STR1 wherein R represents specific diverse substituents, for example, a linear alkadienyl having from 11 to 13 carbon atoms, and R1 and R2 respectively represent H or OH. Examples of specific compounds are 6-[4'-N-(N'-trans,trans 2,4-tridecadienoylglycyl)spicaminyl-amino]purine, and 6-[4'-N-(N'-trans,trans-2,4 dodecadienyoly glycyl) spicaminyl-amino]purine. Comopunds according to this invention are useful as a pharmaceutical for inhibition of a tumor, for example, human colon cancer.
Sphingolipids and glycerolipids. IV. Syntheses and ionophoretic activities of several analogues of soya-cerebroside II, a calcium ionophoretic sphingoglycolipid isolated from soybean
Shibuya,Kurosu,Minagawa,Katayama,Kitagawa
, p. 1534 - 1544 (2007/10/02)
For examination of the structure-activity relationship five analogues [(2'R)-2'-hydroxypalmitoyl (3), palmitoyl (4), (2'S)-2'-hydroxypalmitoyl (5), β-D-galactosyl (6), and 8,9-dihydro (7) relevancies] of soya-cerebroside II (2), which is a calcium ionopho
Synthesis and Biological Activity of the Isomers and Analogs of (4E,8E,2S,3R,2'R)-N-2'-Hydroxyhexadecanoyl-9-methyl-4,8-sphingadienine, the Ceramide Portion of the Fruiting-inducing Cerebroside in a Basidiomycete Schizophyllum commune
Funaki, Yuji,Kawai, Genshiro,Mori, Kenji
, p. 615 - 624 (2007/10/02)
The title compounds were synthesized by employing 2-aminohexadecanoic acid and serine as the chiral sources, and served for an assay of fruiting-inducing activity on Schizophyllum commune.The structure-bioactivity relationship among closely related synthetic ceramides is discussed.
SYNTHESIS OF (4E,8E,2S,3R,2'R)-N-2'-HYDROXYHEXADECANOYL-9-METHYL-4,8-SPHINGADIENINE, THE CERAMIDE PORTION OF THE FRUITING-INDUCING CEREBROSIDE IN A BASIDIOMYCETE SCHIZOPHYLLUM COMMUNE, AND ITS (2R,3S)-ISOMER
Mori, Kenji,Funaki, Yuji
, p. 2369 - 2378 (2007/10/02)
A synthesis of the natural enantiomer as well as its diastereomer of the title compound was accomplished, confirming the structure proposed for the fruiting-inducing cerebroside of Schizophyllum commune.
