939798-77-3

Upstream product

• 911669-03-9 L-(+)-1,1'-methylenebis[5-oxo-2-pyrrolidinecarboxylic acid ethyl ester] 
• 16473-66-8 L-(+)-1,1'-methylenebis[5-oxo-2-pyrrolidinecarboxylic acid] 
• 98-79-3 L-Pyroglutamic acid 
• 939798-78-4 L-(+)-1,1'-methylenebis[5-hydroxymethyl-2-pyrrolidinone] 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant academic research and scientific papers

An optimised synthetic approach to a chiral derivatising agent and the utilisation of a dimerisation reaction in the synthesis of a novel C2-symmetric diphosphine ligand

We report an optimised synthetic approach to the chiral derivatising agent (5R)-methyl-1-(chloromethyl)-2-pyrrolidinone. In addition, the observation of an unwanted dimerisation product is turned to our advantage by providing a method for the synthesis of a new class of C2-symmetric chiral diphosphine.