164931-75-3Relevant academic research and scientific papers
Immobilization of heterobimetallic multifunctional asymmetric catalyst
Arai, Takayoshi,Hu, Qiao-Sheng,Zheng, Xiao-Fan,Pu, Lin,Sasai, Hiroaki
, p. 4261 - 4263 (2000)
(equation presented) Immobilization of an asymmetric AlLibis(binaphthoxide) catalyst (ALB) is described. The immobilized ALBs (poly-ALBs) are readily prepared from polymeric BINOL derivatives and LiAlH4. The combined use of 9 mol % of BuLi with
Novel enantiomer-switching catalysts for asymmetric reductions and Michael reactions
Narasimhan,Velmathi,Balakumar,Radhakrishnan
, p. 719 - 721 (2001)
The newly developed chiral ligands 1 and 2 show opposite enantioselectivity in prochiral ketone reduction and Michael addition reactions resulting in the production of both enantiomers of the products in good chemical and enantiomeric yield.
Polymer-supported bisBINOL ligands for the immobilization of multicomponent asymmetric catalysts
Sekiguti, Tetuya,Iizuka, Yoshimasa,Takizawa, Shinobu,Jayaprakash, Doss,Arai, Takayoshi,Sasai, Hiroaki
, p. 2647 - 2650 (2003)
(Matrix presented) Polymer-supported bisBINOL ligands were successfully utilized for the immobilization of multicomponent asymmetric catalysts. The polymer-supported Al-Li-bis(binaphthoxide) (ALB) catalyst was more effective than the dendrimer-supported A
Immobilization of asymmetric multifunctional catalysts on an insoluble polymer
Matsunaga,Ohshima,Shibasaki
, p. 8473 - 8478 (2000)
Polymer-supported linked-BINOL was synthesized to immobilize asymmetric catalysts with two BINOL units. The advantage of the polymer-supported linked-BINOL over randomly polymer-supported BINOL was confirmed by asymmetric Michael reaction. A novel polymer
Development of new methods toward efficient immobilization of chiral catalysts
Takizawa, Shinobu,Patil, Mahesh L.,Marubayashi, Kazuyoshi,Sasai, Hiroaki
, p. 6512 - 6528 (2007)
BINOL moieties are efficiently immobilized onto the surface of a micelle-derived spherical polymer and a monolayer-protected Au cluster (Au-MPC). Ti-BINOLate complexes generated from the BINOL immobilized polymer and Au-MPC are found to promote catalytic
Synthesis and catalytic applications of soluble polymer-supported BINOL
Jayaprakash, Doss,Sasai, Hiroaki
, p. 2589 - 2595 (2001)
The synthesis of a soluble polymer containing BINOL residues is described. Titanium-BINOLate and AlLibis(binaphthoxide) catalysts are easily generated from this polymer and applied to the asymmetric reaction of Et2Zn with benzaldehyde and the a
A dendrimer-supported heterobimetallic asymmetric catalyst
Arai, Takayoshi,Sekiguti, Tetuya,Iizuka, Yoshimasa,Takizawa, Shinobu,Sakamoto, Shigeru,Yamaguchi, Kentaro,Sasai, Hiroaki
, p. 2083 - 2087 (2002)
Plural ligands consisting of catalysts such as AlLibis(binaphthoxide) complex (ALB) and GaNabis(binaphthoxide) complex (GaSB) are effectively introduced onto the periphery of a dendrimer. The resulting dendrimer-supported heterobimetallic catalysts promot
Metal-Bridged Polymers as Insoluble Multicomponent Asymmetric Catalysts with High Enantiocontrol: An Approach for the Immobilization of Catalysts without Using any Support
Takizawa, Shinobu,Somei, Hidenori,Jayaprakash, Doss,Sasai, Hiroaki
, p. 5711 - 5714 (2003)
Immobile without support: The first synthesis of chiral Al-bridged and Ti-bridged polymers by a metal-mediated self-assembly of (R,R)-6,6′ -bi(binol) (binol = 1,1′-bi-2-naphthol), which bears two pairs of phenolic hydroxy groups at the opposite sides in t
"Catalyst analogue": A concept for constructing multicomponent asymmetric catalysts (MAC) by using a polymer support
Arai, Takayoshi,Sekiguti, Tetuya,Otsuki, Kazuhiro,Takizawa, Shinobu,Sasai, Hiroaki
, p. 2144 - 2147 (2003)
Big MAC news! A new concept for constructing multicomponent asymmetric catalysts (MACs) is proposed by use of a stable "catalyst analogue". After copolymerization of a catalyst analogue having olefinic moieties with a monomer (e.g., methyl methacrylate),
Helical foldamer-catalyzed enantioselective 1,4-addition reaction of dialkyl malonates to cyclic enones
Umeno, Tomohiro,Ueda, Atsushi,Doi, Mitsunobu,Kato, Takuma,Oba, Makoto,Tanaka, Masakazu
supporting information, (2019/11/13)
The introduction of a five-membered ring α,α-disubstituted α-amino acid into L-Leu-based heptapeptides preferentially induced right-handed (P) helical structures. Using 5 ～ 20 mol% of a single helical foldamers-catalyst, enantioselective 1,4-addition reactions of dialkyl malonates to cycloalk-2-enones (5 ～ 7 rings) proceeded to give chiral 3-substituted cycloalkanones with 94 ～ 99% ee in moderate chemical yields, regardless of the ring size of substrates.
