16507-10-1

Upstream product

• 58400-71-8 2-Cyclohexenyl-2-diazopropionat 
• 822-67-3 Cyclohex-2-enol 
• 814-68-6 acryloyl chloride 
• 79-10-7 acrylic acid 
• 110-83-8 cyclohexene 

Downstream Products

• 88708-23-0 2-[2-cyclohexenyl]propanoic acid 

Relevant academic research and scientific papers

Allyl acrylate compound for preparing spiro-lactone, spiro-lactone and preparation method of spiro-lactone

The invention relates to an allyl acrylate compound for preparing spiro lactone, the spiro lactone and a preparation method of the spiro lactone, and belongs to the technical field of organic synthesis. The allyl acrylate compound for preparing spirolactone has a structural formula shown as a formula II. A carbon-carbon double bond in allyl ester is located in a ring, the carbon-carbon double bond is separated from ester by a carbon atom, and a carbon-carbon double bond in acrylic acid is adjacent to a carbonyl group of an ester group, so that the compound can be activated under a photocatalysis effect and is further converted into spiro lactone. The invention also provides the preparation method of the spiro-lactone. The spiro-lactone is obtained by carrying out photocatalytic reaction on the allyl acrylate compound. The method does not need to introduce any catalyst and additive, belongs to a green chemical method which is green, high in atom economy, low in toxicity, low in price, mild in reaction condition and environment-friendly, and has important significance on development of green reaction.

Dual Photoredox/Nickel-Catalyzed Three-Component Carbofunctionalization of Alkenes

The potential of merging photoredox and nickel catalysis to perform multicomponent alkene difunctionalizations under visible-light irradiation is demonstrated here. Secondary and tertiary alkyl groups, as well as sulfonyl moieties can be added to the terminal position of the double bond with simultaneous arylation of the internal carbon atom in a single step under mild reaction conditions. The process, devoid of stoichiometric additives, benefits from the use of bench-stable and easy-to-handle reagents, is operationally simple, and tolerates a wide variety of functional groups.

Evidence for the intermediacy of (η3-allyl)palladium complexes in the palladium-catalyzed acryloxylation of cycloalkenes: Unexpected oxidation of 1,5-cyclooctadiene

Palladium-catalyzed acryloxylation of several cycloalkenes in the presence of the Pd(OAc)2/p-benzoquinone/MnO2 catalytic system is reported. This oxidation reaction yields allylic acrylates as the sole products through the intermedia

Intramolecular acryloxypalladation. Stereospecific synthesis of ring fused unsaturated α-methylene γ-butyrolactones.

The intramolecular carboxypalladation reaction [Pd(OAc)2 5 mol%, NaOAc 2 eq, O2, THF, rt] of 2-(2-Cycloalken-1-yle) propenoic acids yields ring fused α-methylene γ-butyrolactones with good yields. (75-80%).

Acryloxy and Methacryloxy Palladation of Alkenes

Acrylic and methacrylic esters can be obtained in one step from alkenes using a Pd(OAc)2/benzoquinone/MnO2 catalyst; with acrylic acid and a suitable alkene, it is also possible to obtain α-methylene γ-lactones in one step.