16537-17-0Relevant articles and documents
A fast and practical synthesis of tert-butyl esters from 2-tert-butoxypyridine using boron trifluoride·diethyl etherate under mild conditions
La, Minh Thanh,Kim, Hee-Kwon
, p. 3748 - 3754 (2018/05/28)
A practical direct preparation of tert-butyl esters from 2-tert-butoxypyridine has been developed. This system features the use of boron trifluoride·diethyl etherate in toluene solvent to rapidly achieve the reaction at room temperature. Using this reaction protocol, a variety of tert-butyl esters were synthesized from several different carboxylic acids at high yields. This practical procedure provides a promising and effective approach to the protection of carboxylic acids with a tert-butyl group.
A direct and sustainable synthesis of tertiary butyl esters enabled by flow microreactors
Degennaro, Leonardo,Maggiulli, Daniela,Carlucci, Claudia,Fanelli, Flavio,Romanazzi, Giuseppe,Luisi, Renzo
supporting information, p. 9554 - 9557 (2016/08/01)
Tertiary butyl esters find large applications in synthetic organic chemistry. A straightforward method for the direct introduction of the tert-butoxycarbonyl group into a variety of organic compounds has been developed using flow microreactor systems. The resultant flow process was more efficient, versatile and sustainable compared to the batch.
Transition-metal-free alkoxycarbonylation of aryl halides
Zhang, Hua,Shi, Renyi,Ding, Anxing,Lu, Lijun,Chen, Borui,Lei, Aiwen
supporting information, p. 12542 - 12545 (2013/02/23)
Transitions: The title reaction has been developed for the synthesis of a variety of tert-butyl benzoates by employing 1,10-phenanthroline as an additive. Various functional groups were tolerated and heteroaryl iodides were also suitable substrates. Preli
