16538-65-1

Basic information

• Product Name: Silane, [(dichloromethylsilyl)methyl]trimethyl-
• CAS NO: 16538-65-1
• Molecular Formula: C5H14Cl2Si2
• Molecular Weight: 201.243
• Mol File: 16538-65-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Silane, [(dichloromethylsilyl)methyl]trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, [(dichloromethylsilyl)methyl]trimethyl-(16538-65-1)
• EPA Substance Registry System: Silane, [(dichloromethylsilyl)methyl]trimethyl-(16538-65-1)

Safety Data

• Hazardous Substances Data: 16538-65-1(Hazardous Substances Data)

Upstream product

• 1440146-80-4 methylbis(2,4,6-trimethoxyphenyl)[(trimethylsilyl)methyl]silane 

Downstream Products

• 4459-30-7 1,1,3,5,5-pentamethyltrisiloxane 
• 31397-48-5 Me₃SiCH₂SiMe₂OSiMe₂H 
• 992-94-9 methylsilane 
• 1111-74-6 dimethylsilane 
• 993-07-7 trimethylsilan 
• 993-00-0 chloro-methyl-silane 
• 814-98-2 1,1,2,2-tetramethyldisilane 
• 870-26-8 1,2-dimethyldisilane 

Relevant articles and documents

Synthesis of silicon-functionalized (silylmethyl)silanes and-dichlorocarbosilanes using the TMOP (2,4,6-trimethoxyphenyl) protecting group: (TMOP)Me2SiCH2Cl and (TMOP) 2MeSiCH2Cl as reagents to introduce the ClMe 2SiCH2, MeOMe2SiCH2, or Cl2MeSiCH2 group by nucleophilic substitution at silicon

In this study, the synthetic potential of the 2,4,6-trimethoxyphenyl (TMOP)-substituted (chloromethyl)silanes (TMOP)Me2SiCH2Cl (1) and (TMOP)2MeSiCH2Cl (2) for the preparation of Si-functionalized (silylmethyl)silanes and α,ω-dichlorocarbosilanes (with skeletons consisting of alternate carbon and silicon atoms) was investigated. Compounds 1 and 2 were used as reagents to introduce the ClMe 2SiCH2, MeOMe2SiCH2, or Cl 2MeSiCH2 group by nucleophilic substitution at silicon. The three-step synthetic method involves the (i) transformation of 1 and 2 into (TMOP)Me2SiCH2MgCl, (TMOP)Me2SiCH 2Li, (TMOP)2MeSiCH2MgCl, and (TMOP) 2MeSiCH2Li, respectively, (ii) reaction of these nucleophiles with chloro- or methoxysilanes, and (iii) subsequent selective cleavage of the TMOP protecting group with HCl/Et2O or MeOH/[CF 3COOH]. Using this method, the following compounds were prepared: ClMe2SiCH2SiMe3 (3), ClMe2SiCH 2SiMe2Cl (4), ClMe2SiCH2SiMeCl 2 (5), ClMe2SiCH2SiCl3 (6), ClMe2SiCH2Si(OMe)3 (7), MeOMe 2SiCH2Si(OMe)3 (8), Cl2MeSiCH 2SiMe3 (9), Me2Si(CH2SiMe 2Cl)2 (10), and Me2Si(CH2SiMe 2CH2SiMe2Cl)2 (11).