165381-36-2Relevant academic research and scientific papers
2'-O-aminopropyl ribonucleotides: A zwitterionic modification that enhances the exonuclease resistance and biological activity of antisense oligonucleotides
Griffey,Monia,Cummins,Freier,Greig,Guinosso,Lesnik,Manalili,Mohan,Owens,Ross,Sasmor,Wancewicz,Weiler,Wheeler,Cook
, p. 5100 - 5109 (1996)
Oligonucleotides containing 2'-O-aminopropyl-substituted RNA have been synthesized. The 2'-O-(aminopropyl)adenosine (APA), 2'-O- (aminopropyl)cytidine (APC), 2'-O-(aminopropyl)-guanosine (APG), and 2'-O- (aminopropyl)uridine (APU) have been prepared in hi
