16555-77-4

Usage

Uses

Used in Enzyme-Catalyzed Reactions:
ALPHA-HYDROXYHIPPURIC ACID is used as a substrate in the synthesis of benzamide through enzyme-catalyzed dealkylation reactions. This application is particularly relevant in the field of organic chemistry and pharmaceutical synthesis, where enzyme-catalyzed reactions offer a more efficient and environmentally friendly approach to producing desired compounds.

InChI:InChI=1/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)/p-1

Upstream product

• 1199-01-5 2-phenylazlactone 
• 546-67-8 lead(IV) tetraacetate 
• 71-43-2 benzene 
• 7726-95-6 bromine 
• 107-06-2 1,2-dichloro-ethane 
• 495-69-2 Hippuric Acid 
• 56-23-5 tetrachloromethane 
• 55-21-0 benzamide 
• 563-96-2 2,2-dihydroxyacetic acid 
• 298-12-4 Glyoxilic acid 

Downstream Products

• 58486-98-9 benzoyl-DL-phenacylglycine 
• 62804-58-4 methyl 2-benzoylamino-4-oxopentanoate 
• 58486-97-8 2-Benzamido-4-oxopentansaeure,N-Benzoyl-β-acetylalanin 
• 56674-30-7 2-(benzamido)-2-(4-methoxyphenyl) acetic acid 
• 72761-73-0 1-benzoylamino-(ethylthio)acetic acid 
• 29670-63-1 N-benzoyl-2-phenylglycine 
• 126746-22-3 Benzoylamino-(4-isopropyl-phenyl)-acetic acid 
• 120667-33-6 α-(benzoylamino)-4-(3-bromopropyl)benzeneacetic acid 
• 103197-02-0 N-benzoyl-2-(2-bromoethoxy)-5-fluorophenylglycine 
• 112654-53-2 Benzoylamino-hydroxy-thioacetic acid S-[(E)-3-(4-methoxy-phenyl)-allyl] ester 
• 103197-03-1 N-benzoyl-2-(2-chloroethoxy)-5-fluorophenylglycine 
• 103197-04-2 N-benzoyl-2-(2-iodoethoxy)-5-fluorophenylglycine 
• 1134785-08-2 (R,S)-N-benzoyl-2-((2R)-1-bromopropoxy)-5-fluorophenylglycine 
• 111503-24-3 2-(benzoylamino)-2-<2-<(1R)-2-bromo-1-methylethoxy>-4-chloro-5-fluorophenyl>acetic acid 

Relevant academic research and scientific papers

Hydrogen tunneling in peptidylglycine α-hydroxylating monooxygenase

The temperature dependence of the primary and secondary intrinsic isotope effects for the C-H bond cleavage catalyzed by peptidylglycine α-hydroxylating monooxygenase has been determined. Analysis of the magnitude and Arrhenius behavior of the intrinsic isotope effects provides strong evidence for the use of tunneling as a primary catalytic strategy for this enzyme. Modeling of the isotope effect data allows for a comparison to the hydrogen transfer catalyzed by soybean lipoxygenase in terms of environmental reorganization energy and frequency of the protein vibration that controls the hydrogen transfer. Copyright

Methods for the synthesis of dicarba bridges in organic compounds

The present invention relates to methods for forming dicarba bridges in organic compounds. This involves the use of a pair of complementary metathesisable groups on the organic compound, and subjecting the compound to cross-metathesis under microwave radiation conditions. In an alternative, the compounds contain a turn-inducing group between the pair of cross-metathesisable groups to facilitate the cross-metathesis.

Investigations on the synthesis and chemiluminescence of novel 2-coumaranones

Optimized syntheses of 2-coumaranone derivatives and, based thereon, several new representatives of this class of substances are described. They show a clearly visible chemiluminescence under the exposure of a strong base and in the presence of oxygen. The wavelength and intensity of the light emitted depends on both the substituents on the benzo annealed, as well as on the type of base used. A mechanism is presented in which a delocalized enolate is postulated as a key intermediate. ARKAT-USA, Inc.

Conotoxin analogues and methods for synthesis of intramolecular dicarba bridge-containing peptides

According to the present invention, there is provided a range of new conotoxin derivatives and methods for synthesizing these analogues and other intramolecular dicarba bridge-containing peptides, including dicarba-disulfide bridge-containing peptides.