16601-40-4

Basic information

• Product Name: S-benzyl phenylmethanesulfonothioate
• Synonyms: S-Benzyl phenylmethanesulfonothioate; S-Benzyl phenylmethanethiosulfonate
• CAS NO: 16601-40-4
• Molecular Formula: C₁₄H₁₄O₂S₂
• Molecular Weight: 278.3898
• Mol File: 16601-40-4.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 482°C at 760 mmHg
• Flash Point: 245.3°C
• Density: 1.277g/cm³
• Vapor Pressure: 5.57E-09mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: S-benzyl phenylmethanesulfonothioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-benzyl phenylmethanesulfonothioate(16601-40-4)
• EPA Substance Registry System: S-benzyl phenylmethanesulfonothioate(16601-40-4)

Safety Data

• Hazardous Substances Data: 16601-40-4(Hazardous Substances Data)

Upstream product

• 150-60-7 dibenzyl disulphide 
• 621-08-9 Dibenzyl sulfoxide 
• 13402-51-2 benzyl benzothioate 
• 64-17-5 ethanol 
• 6035-47-8 sodium hydroxymethanesulfinate dihydrate 
• 100-44-7 benzyl chloride 
• 100-53-8 phenylmethanethiol 
• 68776-77-2 Methoxycarbonylbenzylsulfoxid 
• 538-74-9 dibenzyl sulfide 
• 1589-82-8 phenylmagnesium bromide 
• 74491-15-9 4-methyl-4-benzylsulphinylpentan-2-one 
• 7722-84-1 dihydrogen peroxide 
• 64-19-7 acetic acid 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 150-60-7 dibenzyl disulphide 
• 29055-93-4 α,α-bis-benzylsulfanyl-deoxybenzoin 
• 620-32-6 dibenzyl sulfone 
• 5418-20-2 benzaldehyde dibenzyldithioacetal 
• 100-52-7 benzaldehyde 
• 621-08-9 Dibenzyl sulfoxide 
• 969-18-6 1-benzylsulfonyl-2,4-dinitrobenzene 
• 76625-87-1 bis(phenylmethyl) α-disulfone 
• 538-74-9 dibenzyl sulfide 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 100-53-8 phenylmethanethiol 
• 7664-93-9 sulfuric acid 
• 100-87-8 Benzylsulfonic acid 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Synthesis of Symmetrical and Unsymmetrical Thiosulfonates from Disulfides through Electrochemically Induced Disulfide Bond Metathesis and Site-Selective Oxidation

The anodic generation of symmetrical and unsymmetrical thiosulfonates is presented. First, the oxidation of disulfides yielding symmetrical thiosulfonates was realized. The direct synthesis is performed using a simple quasi-divided cell design, whereby using a supporting electrolyte is unnecessary. Its principle was then expanded to the conversion of unsymmetrical disulfides that were generated in situ through metathesis of two symmetrical disulfides. This enables a direct access to unsymmetrical thiosulfonates without any pre-functionalization or elaborate synthesis of the starting materials for the first time. The reaction scope was investigated by converting differently functionalized aliphatic and aromatic disulfides in moderate to very good yields. Furthermore, a sensitivity assessment for an improved reproducibility and a robustness screen to determine the compatibility of the reaction against functional groups were performed.

Preparation method of sulfuryl thioester

The invention provides a preparation method of sulfuryl thioester, which uses mercaptan as a starting material. The hydrogen peroxide is an oxidizing agent, an alkali metal halide or an alkaline earth metal halide is used as an additive to prepare the sulfuryl thioester. The product obtained by the method is high in purity and low in production cost, avoids introducing a metal oxidant, can be used for industrial production, and has a good application prospect.

Selective Oxidation of Sulfides in Flow Chemistry

A packed-bed reactor with oxone has been employed for selective oxidations of sulfur compounds. Various sulfides containing different functional groups are efficiently oxidized to the corresponding sulfoxides without formation of sulfones or other side products.