16619-66-2

Upstream product

• 13146-23-1 copper(I) phenylacetylenide 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 529-28-2 4-iodoanisol 
• 201230-82-2 carbon monoxide 
• 536-74-3 phenylacetylene 
• 578-57-4 2-bromoanisole 
• 26767-06-6 2-(2-methoxyphenyl)-2-oxoacetic acid 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 66644-69-7 ethyl (2-methoxyphenyl)(oxo)acetate 
• 1011297-70-3 2-(2-methoxyphenyl)-2-oxoacetyl chloride 
• 579-74-8 2-Methoxyacetophenone 
• 7436-90-0 2,2-dibromostyrene 
• 100-52-7 benzaldehyde 
• 637-44-5 phenylpropyolic acid 

Downstream Products

• 525-82-6 FLAVONE 
• 98153-12-9 3-iodo-2-phenyl-4H-1-benzopyran-4-one 
• 1183859-96-2 dimethyl (7-methoxy-1-oxo-3-phenyl-1H-inden-2-yl)phosphonate 
• 1332697-99-0 3-(ethylselenyl)-2-phenyl-4H-chromen-4-one 
• 1332697-98-9 3-(butylselenyl)-2-phenyl-4H-chromen-4-one 
• 1332697-97-8 2-phenyl-3-(o-tolylselenyl)-4H-chromen-4-one 
• 1332697-96-7 2-phenyl-3-(4-methylphenylselenyl)-4H-chromone 
• 1332697-94-5 3-(4-chlorophenylselenyl)-2-phenyl-4H-chromen-4-one 
• 1332697-92-3 2-phenyl-3-(phenylselenyl)-4H-chromen-4-one 
• 1332697-93-4 3-(4-fluorophenylselenyl)-2-phenyl-4H-chromen-4-one 
• 1332697-95-6 2-phenyl-3-(3-(trifluoromethyl)phenylselenyl)-4H-chromen-4-one 
• 1420041-43-5 (E)-3-fluoro-1-(2-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 1420041-42-4 (Z)-3-fluoro-1-(2-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 1403761-23-8 3-mercapto-1-(2-methoxyphenyl)-3-phenylprop-2-en-1-one 

Relevant academic research and scientific papers

Organoborane-catalyzed selective 1,2-reduction of alkynones with hydride transfer: Synthesis of benzyl alkynes

Benzyl alkynes are important organic building blocks in organic synthesis. We report herein a B(C6F5)3-catalyzed site-selective 1,2-reduction of readily available alkynones to access benzyl alkyne derivatives. Under the de

Solvent switchable Pd/DNA catalyst in carbonylative Sonogashira coupling

Palladium catalysts immobilized on DNA (Pd/DNA) were applied for the first time in the carbonylative Sonogashira coupling, at 1 atm of CO. Different alkynones were obtained with a high yield in DMF. In the presence of water, the selectivity completely changed and diaryl alkynes, typical Sonogashira products, were selectively formed. In addition to Pd/DNA, soluble palladium species also participated in the catalytic process. The stability of the catalytic system increased after the addition of DNA excess.

Synthesis and Characterization of Ag@g?C3N4 and Its Photocatalytic Evolution in Visible Light Driven Synthesis Of Ynone

The primary aim of this work is to synthesize photocatalyst to promote the synthesis of ynones. In this context, we synthesized AgNPs@g?C3N4 nanocomposite. The nanocomposite was characterized by using SEM, HR-TEM, XRD, EDS, ICP-AES,

Base-Promoted Michael Addition/Smiles Rearrangement/ N-Arylation Cascade: One-Step Synthesis of 1,2,3-Trisubstituted 4-Quinolones from Ynones and Sulfonamides

A general, practical, and environmentally friendly protocol to synthesize 1,2,3-trisubstituted 4-quinolones from readily available ynones and sulfonamides was developed. The construction of one C?C bond and two C?N bonds via cleavage of one N?S, one C?S,

Synthesis of 3-(2-quinolyl) chromones from ynones and quinoline: N -oxides via tandem reactions under transition metal- And additive-free conditions

A novel method for the synthesis of 3-(2-quinolyl) chromones through a tandem [3+2] cycloaddition/ring-opening/O-arylation from ynones and quinoline N-oxides has been developed. This protocol proceeds under transition metal- and additive-free conditions a

Pyrene marked benzimidazole n-heterocyclic carbene palladium metal complex and preparation and application thereof

The invention relates to a pyrene marked benzimidazole n-heterocyclic carbene palladium metal complex. The pyrene marked benzimidazole n-heterocyclic carbene palladium metal complex is prepared from benzimidazole serving as a skeleton and pyridine serving

Ring Closing Metathesis Approach for the Synthesis of o-Terphenyl Derivatives

A linear synthesis of o-terphenyl derivatives has been delineated using ring closing metathesis (RCM) as the key step. In this approach, benzil derivatives upon allyl Grignard addition provides diphenyl-1,2-diallyl dihydroxy derivatives which undergo ring closing metathesis to afford tetrahydro terphenyl derivatives. Aromatization-driven dehydration then leads to a diverse set of electron rich and electron deficient o-terphenyls. Furthermore, oxidative coupling of electron rich o-terphenyls provides the corresponding triphenylene derivatives.

Base-Controlled Divergent Synthesis of 5-Cyanobenzoxepines and Benzofuro[2,3- b]pyridines from 2-Bromophenylacetonitriles and Ynones

An effective base-controlled divergent annulation reaction of 2-bromophenylacetonitriles and ynones has been developed. Various functionalized 5-cyanobenzoxepines and benzofuro[2,3-b]pyridines were obtained with a broad substrate scope and high regioselec

Synthesis of α,β-alkynyl ketones via the nickel catalysed carbonylative Sonogashira reaction using oxalic acid as a sustainable C1 source

An efficient and economic nickel-dppb catalyzed, carbonylative Sonogashira cross-coupling reaction was demonstrated to provide rapid access to various α,β-alkynyl ketones from aryl iodides and terminal alkynes using oxalic acid as the ex situ C1 source in a double vial (DV) system. Notably, the role of the ligand in combination with the Ni catalyst for the selective formation of carbonylative Sonogashira products was investigated and supported with control experiments. Yet, no reports are available for carbonylative Sonogashira coupling by using a CO-surrogate under Ni-catalyzed conditions. In this process, for the first time, oxalic acid is used as an ex situ solid, bench stable, easy to handle and efficient CO surrogate in a DV-system for the carbonylative Sonogashira coupling reaction with vast substrate scope.

Silver-catalyzed Double Decarboxylative Radical Alkynylation/Annulation of Arylpropiolic Acids with α-keto Acids: Access to Ynones and Flavones under Mild Conditions

Ynones are privileged building blocks in various organic syntheses of heterocyclic derivatives due to their multifunctional nature, and flavones are an important class of natural products with a wide range of biological activities. We describe the catalytic double decarboxylative alkynylation of arylpropiolic acids with α-keto acids. With Ag(I)/persulfate as the catalysis system, the valuable ynones bearing various substituents could be easily obtained. The introduction of hydroxyl substituent on ortho-site of α-keto acids make this strategy further applicable to the construction of flavone derivatives via heteroannulation in moderate to good yields with a similar silver-catalyzed system. The reactions proceed under relatively mild reaction conditions and tolerate a wide variety of functional groups. Control experiments indicated that both the reactions undergo radical processes. (Figure presented.).