1666-85-9

Basic information

• Product Name: 1,3,4-TRIPHENYL-1H-PYRAZOLE
• Synonyms: 1,3,4-TRIPHENYL-1H-PYRAZOLE;1,3,4-triphenylpyrazole
• CAS NO: 1666-85-9
• Molecular Formula: C₂₁H₁₆N₂
• Molecular Weight: 296.37
• Product Categories: pharmacetical
• Mol File: 1666-85-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 443 °C at 760 mmHg
• Flash Point: 221.7 °C
• Appearance: /
• Density: 1.08 g/cm³
• Vapor Pressure: 1.25E-07mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 1,3,4-TRIPHENYL-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-TRIPHENYL-1H-PYRAZOLE(1666-85-9)
• EPA Substance Registry System: 1,3,4-TRIPHENYL-1H-PYRAZOLE(1666-85-9)

Safety Data

• Hazardous Substances Data: 1666-85-9(Hazardous Substances Data)

Usage

General Description

1,3,4-triphenyl-1H-pyrazole is a chemical compound with a molecular formula C21H15N3. It is a type of pyrazole derivative and belongs to the class of organic compounds known as phenylpyrazoles. 1,3,4-TRIPHENYL-1H-PYRAZOLE is used in various research and industrial applications, including as a building block in the synthesis of other organic compounds. It has been studied for its potential pharmaceutical and biological activities, and its potential use in the development of new drugs. 1,3,4-triphenyl-1H-pyrazole is also known for its ability to exhibit fluorescence and has been used in the development of fluorescent sensors for detecting metal ions.

InChI:InChI=1/C21H16N2/c1-4-10-17(11-5-1)20-16-23(19-14-8-3-9-15-19)22-21(20)18-12-6-2-7-13-18/h1-16H

Upstream product

• 1190837-94-5 4-bromo-1-phenyl-1H-pyrazol-3-yl trifluoro methanesulfonate 
• 98-80-6 phenylboronic acid 
• 21306-38-7 7-phenyl-1,7-diaza-bicyclo<2.2.1>heptane-exo-2,3-exo-5,6-tetracarboxylic acid bisphenylimide 
• 501-65-5 diphenyl acetylene 
• 100-52-7 benzaldehyde 
• 100-63-0 phenylhydrazine 
• 5153-67-3 nitrostyrene 
• 588-64-7 (E)-1-benzylidene-2-phenylhydrazine 
• 108-86-1 bromobenzene 
• 77169-12-1 1,3-diphenyl-1H-pyrazole-4-carboxylic acid 
• 583-11-9 N-(1-phenylethylidene)phenylhydrazine 
• 21487-45-6 1,3-diphenyl-4-formylpyrazole 
• 98-86-2 acetophenone 
• 591-50-4 iodobenzene 

Relevant articles and documents

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Synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines via cascade imination/intramolecular decarboxylative coupling

A general approach for the synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines is described involving the implementation of a cascade imination/intramolecular decarboxylative coupling between potassium 2-amino(hetero)benzoates and 2-haloarylaldehydes. The reactions of pyrazole-based substrates require a Pd-Cu bimetallic system for superior yields whereas the thienyl-based substrates afford the products in excellent yields with a Pd-catalyst only.

Regioselective rapid analog synthesis of 1,3-(or 1,5-)diphenyl-4-aryl/ heteroaryl-5-(or 3-)(methylthio)pyrazoles via Suzuki cross-coupling

Regioselective routes for the synthesis of 1,3-(or 1,5-)diphenyl-4-aryl/ heteroaryl-5-(or 3-)(methylthio)pyrazoles via Suzuki cross-coupling of 4-bromo (or 4-iodo)-1,3-(or 1,5-)diphenyl-5-(or 3-)(methylthio)pyrazoles have been reported.