166820-35-5

Upstream product

• 100159-47-5 1-(benzyloxy)pyrazole 
• 100-39-0 benzyl bromide 

Downstream Products

• 217313-05-8 1,1'-Bis(benzyloxy)-5,5'-bipyrazolyl 
• 365562-80-7 1,1'-Bis(benzyloxy)-4,4'-diiodo-5,5'-bipyrazolyl 
• 365562-82-9 1,1'-Bis(benzyloxy)-4,4'-diphenyl-5,5'-bipyrazolyl 

Relevant academic research and scientific papers

Synthesis of 5-Substituted 1-Hydroxypyrazoles through Directed Lithiation of 1-(Benzyloxy)pyrazole

1-Hydroxypyrazoles have been converted to 1-(benzyloxy), , , and (silyloxy)pyrazoles. 1-(Benzyloxy)pyrazole was lithiated selectively in the 5-position.Subsequent reaction with electrophiles gives rise to 1-(benzyloxy)pyrazole with carbon, halogen, silicon, sulfur, or tin substituents at the 5-position. 1-(Benzyloxy)pyrazoles could be debenzylated by hydrogen bromide or hydrogenolysis producing 5-substituted 1-hydroxypyrazoles in high overall yield.