16686-11-6 Usage
Uses
Used in Pharmaceutical Synthesis:
2-(3-Chloropropyl)-1,3-dioxolane is used as a synthetic intermediate for the introduction of the 3-(1,3-dioxolan-2-yl)propyl moiety in the development of pharmaceutical compounds. Its unique structure allows for the creation of complex molecules with potential therapeutic applications.
Used in Chemical Synthesis:
In the chemical industry, 2-(3-Chloropropyl)-1,3-dioxolane is utilized as a key building block in the synthesis of various organic compounds, such as (±)-histrionicotoxin, (±)-histrionicotoxin 235A, 4-iodobutyraldehyde, 5-iodovaleraldehyde, and 5-iodo-2-petanone. Its reactivity and versatility make it a valuable component in the development of new chemical entities.
Used in Synthesis of Corresponding Phosphonates:
2-(3-Chloropropyl)-1,3-dioxolane is also employed in the synthesis of corresponding phosphonates, which are important in the development of new materials and compounds with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 16686-11-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,6,8 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 16686-11:
(7*1)+(6*6)+(5*6)+(4*8)+(3*6)+(2*1)+(1*1)=126
126 % 10 = 6
So 16686-11-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H11ClO2/c7-3-1-2-6-8-4-5-9-6/h6H,1-5H2
16686-11-6Relevant academic research and scientific papers
Synthesis of the tricyclic ABC ring subunit of mazamine A
Li, Shouming,Kosemura, Seiji,Yamamura, Shosuke
, p. 6661 - 6676 (2007/10/03)
A new approach to the construction of the pyrrolo[2, 3 -i] isoquinoline, the core structure of manzamine A, is described.
An improved method for the use of acetal-substituted grignard reagents in organic synthesis
Forbes, Craig P.,Wenteler, George L.,Wiechers, Adriaan
, p. 2353 - 2355 (2007/10/10)
Grignard reagents derived from 2-(3-chloropropyl)-1,3-dioxolan (1) and 2-(3-chloropropyl)-5,5-dimethyl-1,3-dioxan (2) can be prepared in high yield without decomposition. They undergo 1,2-addition to acrylaldehyde to give allylic alcohols (4a and b), which can be oxidized to give monoprotected dicarbonyl compounds.
