167170-11-8Relevant academic research and scientific papers
An access to aza-Freidinger lactams and E-locked analogs
Ottersbach, Philipp A.,Schmitz, Janina,Schnakenburg, Gregor,Gütschow, Michael
, p. 448 - 451 (2013/04/11)
Freidinger lactams, possessing a peptide bond configuration locked to Z, are important key elements of conformationally restricted peptidomimetics. In the present work, the CαHi+1 unit has been replaced by N, leading to novel aza-Fre
Utility of tetrathiomolybdate and tetraselenotungstate: Efficient synthesis of cystine, selenocystine, and their higher homologues
Bhat, Ramakrishna G.,Porhiel, Emmanuel,Saravanan, Vadivelu,Chandrasekaran, Srinivasan
, p. 5251 - 5253 (2007/10/03)
Efficient synthesis of cystine, selenocystine, and their higher homologues like homo and bishomo amino acid derivatives from natural amino acid derivatives using tetrathiomolybdate and tetraselenotungstate reagents under mild and neutral conditions is reported. The generality of the reaction has been studied by capping various groups to amino and carboxyl components of canonical amino acids.
Facile new method for preparation of optically active protected proline
Yamaguchi, Jun-Ichi,Ueki, Masaaki
, p. 621 - 622 (2007/10/03)
Treatment of L-N-protected 2-amino-5-bromopentanoic acid ester, which was prepared from protected L-glutamic acid, with sodium hydride in tetrahydrofuran (THF) proceeded to give the corresponding protected L-proline in high yield. On the other hand, the reaction of 2-aminobutyric acid derivative with sodium hydride gave the 1-aminocyclopropane-1-carboxylic acid derivative.
Azacycle Synthesis via Radical Cyclization of β-Aminoacrylates.
Lee, Eun,Kang, Tae Seop,Joo, Beom Jun,Tae, Jin Sung,Li, Kap Sok,Chung, Cheol Keun
, p. 417 - 420 (2007/10/02)
(Pyrrolidine)- and (piperidine)acetates are efficiently synthesized via radical cyclization of β-aminoacrylates.
