167300-48-3Relevant academic research and scientific papers
Enantioselective "clip-cycle" synthesis of di-, tri- and spiro-substituted tetrahydropyrans
Alomari, Khadra,Sai Pavan Chakravarthy,Duchadeau, Bastien,Ermanis, Kristaps,Clarke, Paul A.
, p. 1181 - 1185 (2022/02/19)
ω-Unsaturated alcohols were "clipped"via alkene metathesis to a thioester activating group, which was followed by a chiral phosphoric acid catalyzed intramolecular oxa-Michael cyclization to yield tetrahydropyrans and spiro-tetrahydropyrans with excellent
Enantio- and Regioselective Palladium(II)-Catalyzed Dioxygenation of (Aza-)Alkenols
Beccalli, Egle Maria,Giofrè, Sabrina,Lo Presti, Leonardo,Molteni, Letizia,Nava, Donatella
supporting information, p. 21723 - 21727 (2021/09/08)
An oxidative Pd-catalyzed intra-intermolecular dioxygenation of (aza-)alkenols has been reported, with total regioselectivity. To study the stereoselectivity, different chiral ligands as well as different hypervalent-iodine compounds have been compared. I
Intramolecular Hydroalkoxylation of Unactivated Alkenes Using Silane-Iodine Catalytic System
Fujita, Shoji,Abe, Masanori,Shibuya, Masatoshi,Yamamoto, Yoshihiko
supporting information, p. 3822 - 3825 (2015/08/18)
A novel catalytic system using I2 and PhSiH3 for the intramolecular hydroalkoxylation of unactivated alkenes is described. NMR study indicated that in situ generated PhSiH2I is a possible active catalytic species. This catalytic system allows an efficient intramolecular hydroalkoxylation of phenyl-, trialkyl-, and 1,1-dialkyl-substituted alkenes as well as a variety of unactivated monoalkyl- and 1,2-dialkyl-substituted alkenes at room temperature. Mechanistic consideration based on significant experimental observations is also discussed.
Efficient intramolecular hydroalkoxylation/cyclization of unactivated alkenols mediated by lanthanide triflate ionic liquids
Dzudza, Alma,Marks, Tobin J.
supporting information; experimental part, p. 1523 - 1526 (2009/09/06)
Lanthanide triflates, Ln(OTf)3, serve as efficient catalysts for the intramolecular hydroalkoxylation (HO)/cyclization of primary/secondary and aliphatic/aromatic hydroxyalkenes in room temperature ionic liquids (RTlLs). Cyclizations are effective in the formation of five-and sixmembered oxygen heterocycles with Markovnikov-type selectivity. Reaction rates exhibit first-order dependence on [Ln3+] and [substrate].
Platinum-catalyzed intramolecular hydroalkoxylation of γ- and δ-hydroxy olefins to form cyclic ethers
Qian, Hua,Han, Xiaoqing,Widenhoefer, Ross A.
, p. 9536 - 9537 (2007/10/03)
Reaction of 2,2-diphenyl-4-penten-1-ol with a catalytic mixture of [PtCl2(H2C=CH2)]2 (1 mol %) and P(4-C6H4CF3)3 (2 mol %) at 70 °C for 24 h led to the isolation of 2-
Alkyl radical cyclisations of methylenecyclopropane derivatives
Destabel, Christine,Kilburn, Jeremy D.,Knight, John
, p. 11267 - 11288 (2007/10/02)
Radical cyclisations of various methylenecyclopropane derivatives have been studied. Cyclisation of diphenylsubstituted (methylenecyclopropyl)butyl radical 10 gave the unexpected cyclohexene 5, via a series of radical rearrangements. In further studies, (
A Novel Sequence of Radical Rearrangements involving the 5-Exo Cyclisation of a 3-(Methylenecyclopropyl)propyl Radical
Destabel, Christine,Kilburn, Jeremy D.
, p. 596 - 598 (2007/10/02)
Radical 10, generated from the corresponding imidazolethiocarbonyl derivative 3 or the phenyl selenide 4, rearranges in a six-step process to give the cyclohexene 5, after reduction; this rearrangement sequence includes the selective 5-Exo cyclisation of
