16744-89-1

Usage

InChI:InChI=1/C7H14O/c1-4-5-6-7(2,3)8/h4,8H,1,5-6H2,2-3H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 60-29-7 diethyl ether 
• 1968-40-7 ethyl 4-pentenoate 
• 109-49-9 5-Hexen-2-one 
• 516-79-0 provitamin D₄ 
• 67-64-1 acetone 
• 186581-53-3 diazomethane 
• 591-80-0 pent-4-enoic acid 
• 75-16-1 methylmagnesium bromide 
• 287-92-3 Cyclopentane 
• 5162-44-7 1-bromo-4-butene 
• 7103-09-5 4-but-1-enylmagnesium bromide 
• 690-94-8 dimethyl(vinylethynyl)carbinol 
• 64-17-5 ethanol 

Downstream Products

• 4049-81-4 2-methyl-1,5-hexadiene 
• 123883-67-0 2,2-Dimethyl-5-phenylselanylmethyl-tetrahydro-furan 
• 4535-54-0 2,2-dimethyl-6-phenyl-tetrahydro-pyran 
• 103348-72-7 4-Chloro-2-methyl-6-phenyl-hexan-2-ol 
• 103348-71-6 6-Chloro-2-methyl-6-phenyl-hexan-2-ol 
• 103348-70-5 6-(4-Methoxy-phenyl)-2,2-dimethyl-tetrahydro-pyran 
• 3123-97-5 dihydro-5,5-dimethyl-2(3H)-furanone 
• 36326-32-6 5,5-Dimethyl-tetrahydro-furan-2-carbaldehyde 
• 24203-50-7 (5,5-dimethyltetrahydrofuran-2-yl)methanol 
• 123314-88-5 2-methylhex-5-en-2-yl hydroperoxide 
• 123314-92-1 (6,6-dimethyl-1,2-dioxan-3-yl)methanol 
• 123314-90-9 bis-(2-methylhex-5-en-2-yl) peroxide 
• 203069-95-8 Diphenyl(2-methylhex-5-en-2-yloxy)silane 
• 374930-39-9 (S_s,S)-allyl tert-butanesulfinamide 

Relevant academic research and scientific papers

Cyclopentanone ring expansion leading to functionalized δ-lactams: Short synthesis of simple sedum alkaloids

Equation Presented Monosubstituted epoxides react with (cyclopentenyloxy) trimethylsilane to afford, after subsequent oxidative fragmentation, a pair of diastereomeric 8-membered iodolactones. When these lactones are separately treated with sodium azide,

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

A concise approach towards the synthesis of WS75624 a and WS75624 B via the cross-metathesis of vinyl-functionalized thiazoles

Synthetic approach towards precursors of WS75624 A and WS75624 B, two potent endothelin converting enzyme (ECE) inhibitors and potential antihypertensive agents, is reported featuring a key cross-metathesis between a vinyl-functionalized thiazole and a terminal olefin. As the two natural products only differ by the nature of their hydroxyalkyl side-chain, our convergent strategy enable the synthesis of key intermediates of both molecules in a limited amount of steps.

Pd(0)-catalyzed oxy- and aminoalkynylation of olefins for the synthesis of tetrahydrofurans and pyrrolidines

The first Pd(0)-catalyzed intramolecular oxy- and aminoalkynylation of nonactivated olefins is reported. The reaction gives access to important tetrahydrofuran and pyrrolidine heterocycles with high diastereoselectivity. The unique synthetic potential of acetylenes is further exploited to access key building blocks for the synthesis of bioactive natural products.

Viability of 4,5-dihydro-1,2,3,4-oxatriazoles reinvestigated

The first procedures to prepare 4-bromo-4-methylpentanal and 4-azido-4-methylpentanal are reported. The latter compound and also the parent 4-azidobutanal do not lead to 4,5-dihydro-1,2,3,4-oxatriazoles by intramolecular 1,3-dipolar cycloaddition, although it was claimed to be so in the literature. The NMR spectroscopic data of such heterocycles reported previously do not agree with those of similar substances and are incompatible with 13C NMR spectroscopic chemical shifts calculated by quantum chemical methods in the presented work. These calculations show furthermore that the intramolecular cycloaddition of 4-azidobutanals to give the title compounds is strongly endothermic and thus most probably not possible.

Organocatalysis in a synthetic receptor with an inwardly directed carboxylic acid

A cavitand functionalized with a Kemp-s triacid derivative was used to catalyze the epoxide ring-opening cyclizations of 1,5-epoxyalcohols. A deep, cylindrical cavity containing electron-rich aromatic walls and an inwardly directed carboxylic acid displayed the necessary characteristics to bind different 1,5-epoxyalcohols and initiate their cyclization reactions. The reactions inside this synthetic receptor occurred in a catalytic and regioselective manner. These results highlight that the arrangement of functionality and unique solvation provided by the structured interiors of natural enzymes can be incorporated into synthetic systems having useful physical and chemical properties. Copyright

NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a and (Rx)n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

Direct lactonization of alkenols via osmium tetroxide-mediated oxidative cleavage

(Matrix presented) A highly efficient, mild, and simple protocol is presented for the tandem OsO4-mediated oxidative cleavage/oxidative lactonization of alkenols to lactones. The protocol couples the OsO 4-catalyzed oxidative cleavage of olefins with Oxone as the co-oxidant with the direct oxidation of aldehydes in alcoholic solvents to their corresponding esters.