167764-30-9Relevant academic research and scientific papers
Solid-phase synthesis utilizing photochemical carbon-sulfur bond cleavage of thioethers
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, (2008/06/13)
A method for photochemical cleavage of carbon-sulfur bonds in conjunction with solid-phase synthesis utilizing a deoxygenated solvent and light to cleave the carbon-sulfur bond from a heterogeneous support. Also disclosed are compounds for use with said p
Solid-Phase Synthetic Methods in Combinatorial Chemistry
Sucholeiki, Irving
, p. 618 - 630 (2007/10/03)
The gel-phase carbon NMR spectra of various polymer supports are evaluated as to their suitability in the production of non-peptide combinatorial libraries. The solid-phase synthesis of biphenyls as scaffolds for the production of combinatorial libraries is also described. Both substituted and unsubstituted trialkylphenyltins were shown to undergo heterogenous palladium-catalyzed Stille coupling with aryl electrophiles to give after photolytic cleavage using the NpSSMpact linker biphenyls containing no residual amide, carboxylic acid, or alcohol appendages.
