167764-53-6Relevant academic research and scientific papers
Efficient microwave-assisted one-pot three-component synthesis of 2,3-disubstituted benzofurans under Sonogashira conditions
Markina, Nataliya A.,Chen, Yu,Larock, Richard C.
, p. 2701 - 2713 (2013/03/28)
An efficient one-pot method for the synthesis of 2,3-disubstituted benzo[b]furans from commercially available 2-iodophenols, terminal acetylenes and aryl iodides has been developed utilizing Sonogashira reaction conditions. After an initial Sonogashira coupling of the 2-iodophenol with the terminal alkyne, cyclization involving the aryl iodide provides the 2,3-disubstituted benzo[b]furan in good to excellent yields. The use of microwave irradiation shortens the reaction times and minimizes the side products. This methodology is especially useful for the construction of libraries of highly substituted benzo[b]furans and their analogues.
Synthesis and study of new paramagnetic resveratrol analogues
Kálai, Tamás,Borza, Erzsébet,Antus, Csenge,Radnai, Balázs,Gulyás-Fekete, Gergely,Fehér, Andrea,Sümegi, Balázs,Hideg, Kálmán
experimental part, p. 7311 - 7317 (2012/01/03)
New resveratrol analogues containing five- and six-membered nitroxides and isoindoline nitroxides were synthesized. These new compounds were compared to resveratrol based on their ABTS radical scavenging ability as well on their capacity to suppress infla
Propiophenone derivatives and process for preparing the same
-
, (2008/06/13)
A propiophenone derivative of the formula (I): wherein OX is a hydroxy group which may optionally be protected, Y is a lower alkyl group, and Z is a beta -D-glucopyranosyl group wherein one or more hydroxy groups may optionally be protected, or a pharmace
The design and synthesis of substituted biphenyl libraries
Pavia, Michael R.,Cohen, Michael P.,Dilley, Garrett J.,Dubuc, Gloria R.,Durgin, Tracy L.,Forman, Frank W.,Hediger, Mark E.,Milot, Guy,Powers, Timothy S.,Sucholeiki, Irving,Zhou, Shulan,Hangauer, David G.
, p. 659 - 666 (2007/10/03)
A novel scaffold system for the generation of diversity libraries has been designed which allows for rapid modification not only of functional groups, but their spatial arrangements as well. The biphenyl scaffold allows for display of three or four divers
