1538-62-1Relevant academic research and scientific papers
Novel mixed metal Ag(I)-Sb(III)-metallotherapeutics of the NSAIDs, aspirin and salicylic acid: Enhancement of their solubility and bioactivity by using the surfactant CTAB
Gkaniatsou,Banti,Kourkoumelis,Skoulika,Manoli,Tasiopoulos,Hadjikakou
, p. 108 - 119 (2015/12/08)
The already known Ag(I)-Sb(III) compound of the formula {Ag(Ph3Sb)3(NO3)} (1) and two novel mixed metal Ag(I)-Sb(III) metallotherapeutics of the formulae {Ag(Ph3Sb)3(SalH)}(2) and {Ag(Ph3Sb)3(Asp)}(3) (SalH2 = salicylic acid, AspH = aspirin or 2-acetylsalicylic acid and Ph3Sb = triphenyl antimony(III)) have been synthesised and characterised by m.p., vibrational spectroscopy (mid-FT-IR), 13C-,1H-NMR, UV-visible (UV-vis) spectroscopic techniques, high resolution mass spectroscopy (HRMS) and X-ray crystallography. Compounds 1,- 3 were treated with the surfactant cetyltrimethylammonium bromide (CTAB) in order to enhance their solubility and as a consequence their bioactivity. The resulting micelles a-c were characterised with X-ray powder diffraction (XRPD) analysis, X-ray fluorescence (XRF) spectroscopy, Energy-dispersive X-ray spectroscopy (EDX), conductivity, Thermal gravimetry-differential thermal analysis (TG-DTA), and atomic absorption. Compounds 1-3 and the relevant micelles a-c were evaluated for their in vitro cytotoxic activity against human cancer cell lines: MCF-7 (breast, estrogen receptor (ER) positive), MDA-MB-231 (breast, ER negative) and MRC-5 (normal human fetal lung fibroblast cells) with sulforhodamine B (SRB) colorimetric assay. The results show significant increase in the activity of micelles compared to that of the initial compounds. Moreover, micelles exhibited lower activity against normal cells than tumor cells. The binding affinity of a-c towards the calf thymus (CT)-DNA, lipoxygenase (LOX) and glutathione (GSH) was studied by the fluorescent emission light and UV-vis spectroscopy.
Reaction of bis(phenylethynyl)itterbium with tetraphenylantimony halides
Zhiltsov,Pimenova,Gushchin,Morgunova
, p. 705 - 707 (2008/02/02)
Phenylethynyl itterbium derivative (PhC≡C)2Yb(THF) 2 reacts with tetraphenylantimony halides in tetrahydrofuran (THF) at room temperature to form triphenylantimony, phenylacetylene, benzene, and phenylethynylitterbium PhC≡CYbX(THF)4 and itterbium YbX 2(THF)4 halides; X = Cl, Br, I. The reduction of the antimony derivative is accompanied with the generation of phenyl and phenylethynyl radicals. Pleiades Publishing, Inc., 2006.
Pd-catalyzed C-arylation of unsaturated compounds with pentavalent triarylantimony dicarboxylates
Moiseev, Dmitry V.,Gushchin, Aleksey V.,Shavirin, Andrey S.,Kursky, Yury A.,Dodonov, Viktor A.
, p. 176 - 184 (2007/10/03)
Triarylantimony (V) derivatives Ar3SbX2 (X = Hal or acyloxy) were prepared by reaction of Ar3Sb with equimolar amounts of a peroxide ROOH (R = t-Bu, H) in the presence of an acid or an anhydride in good to excellent yields. Ar3Sb(O2CR)2 are mild and efficient C-arylation reagents of unsaturated compounds (methyl acrylate, styrene, 2-phenylpropene and acrylonitrile) under palladium catalysis at 50 °C, with PdCl2 being the most effective catalyst. Ar3SbHal2 do not react under these conditions.
Pd(0)-Cu(I)-catalyzed cross-coupling of alkynylsilanes with triarylantimony(V) diacetates
Kang, Suk-Ku,Ryu, Hyung-Chul,Hong, Young-Taek
, p. 736 - 739 (2007/10/03)
The Pd(0)-Cu(1)-catlyzed cross-coupling of alkynylsilanes with triarylantimony(V) diacetates was studied. Direct carbonylative coupling of triarylantimony diacetates with alkynylsilanes was accomplished under atmospheric pressure of carbon monoxide. It wa
Preparation of triarylantimony(V) diacetates and palladium-catalyzed cross-coupling and carbonylative cross-coupling of triarylantimony(V) diacetates and dichlorides with organostannanes
Kang, Suk-Ku,Ryu, Hyung-Chul,Lee, Sang-Woo
, p. 38 - 41 (2007/10/03)
Triarylstibines react with iodobenzene diacetate in dichloromethane to afford triarylantimony(V) diacetates. The cross-coupling and carbonylative cross-coupling of triarylantimony(V) diacetates and dichlorides with organostannanes was accomplished in the presence of PdCl2 (5 mol%) in CH3CN at room temperature.
Hypervalent iodine in synthesis XXXI: Formation of phosphinimines and arsinimines by nitrene route or non-nitrene route
Ou, Wei,Wang, Zhi-Gang,Chen, Zhen-Chu
, p. 2301 - 2309 (2007/10/03)
N-sulfonyltriphenylphosphinimines and N-sulfonyltriphenylarsinimines are prepared by the reaction of triphenylphosphine or triphenylarsine under nitrene-producing conditions with I-N ylide (PhI=NSO2R). Triphenylarsinimines can also be generated by a non-nitrene route from triphenylarsine, iodobenzene diacetate, and sulfonamides via triphenylarsine diacetate, Ph3As(OAc)2.
Electrochemistry of hypervalent compounds - V. Anodic oxidation of trivalent organoantimony and organobismuth compounds
Fuchigami, Toshio,Miyazaki, Motoko
, p. 1979 - 1984 (2008/10/08)
Anodic oxidation of triphenylantimony in the presence of various oxygen nucleophiles or halide ions provided the corresponding hypervalent compounds having Sb - Y bonds (Y = RCOO, F, Cl, Br) in good yields. On the contrary, anodic oxidation of triphenylbi
Synthesis of triphenylantimony (hydroxo)diketonates by oxidative methods
Gushchin, A. V.,Dodonov, V. A.,Usyatinsky, R. I.,Koreshkova, E. R.,Tipanov, B. B.
, p. 1239 - 1241 (2007/10/02)
Triphenylantimony (hydroxo)acetylacetonate, (hydroxo)trifluoroacetylacetonato, and (hydroxo)pivaloyltrifluoroacetonato were prepared in 85-98percent yields by oxidation of triphenylantimony with hydrogen peroxide or tert-butyl hydroperoxide in the presenc
Crystal Structure of 2,2,4,4-Tetrahydro-2,2,2,4,4,4-hexaphenyl-1,3,2,4-dioxadistibetane (Triphenylstibine Oxide Dimer) and Related Compounds
Bordner, Jon,Doak, G. O.,Everett, T. Stephen
, p. 4206 - 4213 (2007/10/02)
The structure of triphenylstibine oxide has long been the subject of considerable controversy in the chemical literature.Crystals, obtained by the slow cooling of a xylene solution of the crystalline form of the compound I, were subjected to a single-crystal X-ray analysis and shown to exist as a dimer with a four-membered ring containing Sb-O-Sb linkages.Molecular weight determinations and the infrared spectrum showed that this structure was unchanged in solution.The oxidation of triphenylstibine with hydrogen peroxide in acetone solution under carefully controlled conditions led to the formation of a cyclic peroxide in which a mole of acetone was incorporated into the molecule II.Its structure was determined by X-ray analysis.A compound III, previously believed to be diphenylstibinic acid anhydride, was a byproduct of this oxidation.An X-ray analysis of this material showed it to be a complex tricyclic compound with four antimony and six oxygen atoms in the rings.In addition to the crystalline form, one or more amorphous forms of triphenylstibine oxide, of unknown structure, have been prepared.The crystal data (Mo Kα, λ=0.71069 Angstroem) are as follows.I: a=10.703(5) Angstroem, b=10.521(5) Angstroem, c=14.225(8) Angstroem, space group P.II: a=18.124(2) Angstroem, b=9.327(1) Angstroem, c=11.390(1) Angstroem, space group Pna21.III: a=11.677(5) Angstroem, b= 9.745(3) Angstroem, c=10.586(6) Angstroem, space group P.
