16798-45-1

Usage

Uses

Used in Pharmaceutical Industry:
Diethyl benzamidomalonate is used as a key intermediate in the synthesis of drugs, specifically for the development of medications aimed at treating cardiovascular and central nervous system disorders. Its chemical properties make it a valuable component in the formulation of these therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, diethyl benzamidomalonate is utilized as a building block in the production of various agrochemicals. Its role in this sector is crucial for the development of effective and targeted agricultural products.
Used in Specialty Chemicals:
Diethyl benzamidomalonate is also employed in the synthesis of specialty chemicals, where its unique properties contribute to the creation of tailored chemical products for specific applications. Its versatility in organic synthesis makes it an essential component in the development of these specialized compounds.
Storage and Handling:
Due to its sensitivity to degradation, diethyl benzamidomalonate is typically handled and stored under controlled conditions to ensure its stability and maintain its effectiveness in the synthesis processes. This careful management is crucial for preserving the compound's integrity and performance in its various applications.

InChI:InChI=1/C14H17NO5/c1-3-19-13(17)11(14(18)20-4-2)12(16)15-10-8-6-5-7-9-10/h5-9,11H,3-4H2,1-2H3,(H,15,16)

Upstream product

• 4504-11-4 (N-hydroxy-anilinomethylene)-malonic acid diethyl ester 
• 10304-53-7 (phenylimino-methylene)-malonic acid diethyl ester 
• 996-82-7 sodium diethylmalonate 
• 103-71-9 phenyl isocyanate 
• 64-17-5 ethanol 
• 996-82-7 sodium diethylmalonate 
• 105-53-3 diethyl malonate 
• 72091-41-9 (Oxomethylen)malonsaeure-diethylester 
• 62-53-3 aniline 
• 65305-78-4 2-(Dicyano-hydroxy-methyl)-malonic acid diethyl ester 
• 3288-00-4 phenylthiocarbamoyl-malonic acid diethyl ester 
• 4504-12-5 ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxaldehyde 
• 100-65-2 N-Phenylhydroxylamine 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 

Downstream Products

• 15580-32-2 malonanilic acid 
• 103-71-9 phenyl isocyanate 
• 10304-53-7 (phenylimino-methylene)-malonic acid diethyl ester 

Relevant academic research and scientific papers

Interrupted aza-Wittig reactions using iminophosphoranes to synthesize 11C-carbonyls

A direct CO2-fixation methodology couples structurally diverse iminophosphoranes with various nucleophiles to synthesize ureas, carbamates, thiocarbamates, and amides, and is amenable for 11C radiolabeling. This methodology is practical, as demonstrated by the synthesis of >35 products and isolation of the molecular imaging radiopharmaceuticals [11C]URB694 and [11C]glibenclamide. This journal is

Indium-Mediated Blaise-Type Reaction of Bromomalonates with Nitriles and Isocyanates

The indium-mediated Blaise-type reaction of bromomalonates with nitriles and isocyanates is described. The choice of the solvent is crucial for the successful reaction; the dependency on dichloromethane proved to be nonplussed. The reaction with nitriles

The Photolysis Of Ethyl 5-Oxo-2-Phenyl-2,5-Dihydroisoxazole-4-Carboxylate In Amines And Alcohols

Ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxylate (1) has been photolysed at 300 nm in a variety of alcohols and amines.The products suggest two competing photolytic pathways: reversible photoisomerisation to a ketene, and a loss of carbon dioxide t

The chemistry of 5-oxodihydroisoxazoles V: The photolysis of 2-phenylisoxazol-5(2H)-one ln alcohols

Ethyl 5-oxo-2-phenyl-2,5-dihydroisoxazole-4-carboxylate (1) has been photolysed in methanol, ethanol, 1-propanol, 2-propanol, 1-butanol, t-butyl alcohol, allyl alcohol and propargyl alcohol, and the products characterised. Two types of photo products are formed: methanetricarboxylic acid derivatives resulting from alcohol capture of the first formed ketene, and 2-alkoxy-3-phenylaminoacrylates, formed by capture, by the alcohol, of the imino-carbene arising from (1) by loss of carbon dioxide.