16802-73-6

Basic information

• Product Name: 2-(Ethylthio)quinazolin-4(3H)-one
• Synonyms: 2-(Ethylthio)quinazolin-4(3H)-one
• CAS NO: 16802-73-6
• Molecular Formula: C₁₀H₁₀N₂OS
• Molecular Weight: 206.26
• Mol File: 16802-73-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 162 °C(Solv: chloroform (67-66-3))
• Boiling Point: 365.4°C at 760 mmHg
• Flash Point: 174.8°C
• Appearance: /
• Density: 1.31g/cm³
• Vapor Pressure: 1.58E-05mmHg at 25°C
• Refractive Index: 1.662
• PKA: 0.35±0.20(Predicted)
• CAS DataBase Reference: 2-(Ethylthio)quinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Ethylthio)quinazolin-4(3H)-one(16802-73-6)
• EPA Substance Registry System: 2-(Ethylthio)quinazolin-4(3H)-one(16802-73-6)

Safety Data

• Hazardous Substances Data: 16802-73-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H10N2OS/c1-2-14-10-11-8-6-4-3-5-7(8)9(13)12-10/h3-6H,2H2,1H3,(H,11,12,13)

Upstream product

• 13906-09-7 2-thioxo-2,3-dihydro-1H-quinazolin-4-one 
• 75-03-6 ethyl iodide 
• 13906-09-7 2-mercapto-3H-quinazolin-4-one 
• 62-53-3 aniline 
• 24774-92-3 N¹-Aethoxycarbonyl-N²-phenylthioharnstoff 
• 74-96-4 ethyl bromide 
• 80947-13-3 N¹-Aethoxycarbonyl-N²-phenyl-5-aethylisothioharnstoff 
• 118-92-3 anthranilic acid 
• 64-67-5 diethyl sulfate 

Downstream Products

• 58803-78-4 4-chloro-2-ethylsulfanylquinazoline 
• 122009-54-5 2-(4-allyl-1-piperazinyl)-4-pentyloxyquinazoline 
• 39213-14-4 2-(4-methylpiperazin-1-yl)-4-phenoxyquinazoline 
• 129112-57-8 2-(4-Benzyl-piperazin-1-yl)-4-phenoxy-quinazoline 
• 129112-39-6 4-(3-Methoxy-phenoxy)-2-(4-methyl-piperazin-1-yl)-quinazoline 
• 129112-56-7 2-(4-Allyl-piperazin-1-yl)-4-phenoxy-quinazoline 
• 129112-55-6 4-Phenoxy-2-(4-propyl-1-piperazinyl)quinazoline 
• 129112-54-5 2-(4-Ethyl-piperazin-1-yl)-4-phenoxy-quinazoline 
• 129112-67-0 2-(4-Methyl-piperazin-1-yl)-4-p-tolyloxy-quinazoline 
• 129664-02-4 4-Pentyloxy-2-(4-pentyl-piperazin-1-yl)-quinazoline; compound with (E)-but-2-enedioic acid 
• 129664-22-8 2-[4-(2-Methyl-allyl)-piperazin-1-yl]-4-pentyloxy-quinazoline; compound with (E)-but-2-enedioic acid 
• 129664-21-7 2-[((E)-4-But-2-enyl)-piperazin-1-yl]-4-pentyloxy-quinazoline; compound with (E)-but-2-enedioic acid 
• 129664-03-5 2-(4-Butyl-piperazin-1-yl)-4-pentyloxy-quinazoline; compound with (E)-but-2-enedioic acid 
• 129664-06-8 4-Pentyloxy-2-piperazin-1-yl-quinazoline; compound with (E)-but-2-enedioic acid 

Relevant articles and documents

Phase-transfer catalyzed alkylation and cycloalkylation of 2-mercaptoquinazolin-4(3H)-one

Solid/liquid phase-transfer catalyzed alkylation of 2-mercaptoquinazolin- 4(3H)-one at 25°C by different organohalogen compounds in the presence of tetrabutylammonium bromide as a catalyst underwent, exclusively, S-monoalkylation or S- and N-, di-, or cyc

QUINAZOLINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES AND OBESITY

The present invention relates to novel quinazoline derivatives effective in lowering blood glucose level and body weight, and a medicine for treatment and/or prevention of diabetes and/or obesity, which comprises the compound as an active ingredient.

SYNTHESIS AND ALKYLATION OF 2-MERCAPTO-4-QUINAZOLONE AND THE FUNGICIDAL ACTIVITIES OF THE COMPOUNDS OBTAINED

A convenient method of obtaining 2-mercapto-4-quinazolone has been developed and the alkylation of its ambidentate anions has been studied.It has been found that they exhibit a dual reactivity in alkylation reactions.It has been shown that alkylated 2-mercapto-4-quinazolones possess a moderate fungicidal activity.