168127-34-2

Basic information

• Product Name: 2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid
• Synonyms: 2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid;2-[4-(2-AMino-4-thiazolyl)phenoxy]acetic Acid;2-(4-(2-Aminothiazol-4-yl)phenoxy)acetic acid
• CAS NO: 168127-34-2
• Molecular Formula: C11H10N2O3S
• Molecular Weight: 250.27
• Mol File: 168127-34-2.mol

Chemical Properties

• Boiling Point: 513°Cat760mmHg
• Flash Point: 264.1°C
• Appearance: /
• Density: 1.431g/cm³
• Vapor Pressure: 2.38E-11mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: 2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid(168127-34-2)
• EPA Substance Registry System: 2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid(168127-34-2)

Safety Data

• Hazardous Substances Data: 168127-34-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid is used as a potential drug candidate for its possible biological activities, which are currently under research. The presence of the thiazole ring and amino group may allow it to interact with biological targets, offering a foundation for the development of new therapeutic agents.
Used in Chemical Synthesis:
In the chemical industry, 2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid is used as a chemical intermediate. Its unique structure, featuring both thiazole and amino groups, makes it a valuable component in the synthesis of various pharmaceuticals, potentially leading to the creation of novel drugs with specific therapeutic effects.
Further research and testing are essential to fully explore the potential uses and properties of 2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid, ensuring its safe and effective application in relevant fields.

InChI:InChI=1/C11H10N2O3S/c12-11-13-9(6-17-11)7-1-3-8(4-2-7)16-5-10(14)15/h1-4,6H,5H2,(H2,12,13)(H,14,15)

Upstream product

• 168127-29-5 [4-(2-Amino-thiazol-4-yl)-phenoxy]-acetic acid ethyl ester 
• 51828-69-4 ethyl (4-acetylphenoxy)-acetate 
• 754231-46-4 ethyl 4-(2-tosyloxyacetyl)phenoxyacetate 
• 1878-81-5 4-acetylphenoxyacetic acid 
• 17356-08-0 thiourea 
• 29936-82-1 ethyl 4-(bromoacetyl)phenoxyacetate 

Relevant articles and documents

Synthesis and hypolipidemic activity of novel 2-(4-(2-substituted aminothiazole-4-yl) phenoxy) acetic acid derivatives

A novel series of aminotihazole compounds possessing phenoxy acetic acid moiety were synthesized. The synthesized compounds were evaluated for their hypolipidemic activity by using high fat diet induced hyperlipidemia in Sprague-Dawley rats.

Anti-herpesvirus compounds and methods for identifying, making and using same

This invention relates to methods for inhibiting herpes replication and for treating herpes infection in a mammal by inhibiting the herpes helicase-primase enzyme complex. This invention also relates to thiazolyphenyl derivatives that inhibit the herpes helicase-primase and to pharmaceutical compositions comprising the thiazolylphenyl derivatives, to methods of using and methods of producing the thiazolylphenyl derivatives.

Use of benzene in the synthesis of ethyl 4-(2-substituted amino-4-thiazolyl)phenoxyacetates and acids as antiinflammatory agents

Synthesis of ethyl 4-(2-substituted amino-4-thiazolyl)phenoxyacetates has been accomplished by benzene mediated approach involving condensation of 4-(2-tosyloxyacetyl)phenoxyacetate with appropriate thioureas as well as by the Hantzsch thiazole synthesis using ethyl 4-(2-bromoacetyl)phenoxyacetate.These compounds on acidic hydrolysis furnish the corresponding acids.All the compounds have been tested for antiinflammatory activity by carragenin-induced rat paw edema test and one of them has shown good activity.