16825-16-4Relevant articles and documents
Discrimination of stereoisomers by one-dimensional 13C NMR: All 16 stereoisomers of 4-hydroxy-α-tocopherol resolved
Duchateau, Alexander L. L.,Lankhorst, Peter P.,Netscher, Thomas
, (2021/08/26)
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(6R,10R)-6,10,14-TRIMETYLPENTADECAN-2-ONE PREPARED FROM 6,10,14-TRIMETYLPENTADECA-5,9,13-TRIEN-2-ONE OR 6,10,14-TRIMETYLPENTADECA-5,9-DIEN-2-ONE
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, (2014/07/08)
The present invention relates to a process of manufacturing (6R,10R)- 6,10,14-trimetylpentadecan-2-one in a multistep synthesis from a mixture of (5E,9E)-, (5E,9Z)-, (5Z,9E)- and (5Z.9Z)- isomers of 6, 10, 14-trimetylpentadeca- 5,9,13-trien-2-one or 6,10,14-trimetylpentadeca-5,9-dien-2-one. The process is very advantageous in that it forms in an efficient way the desired chiral product from a mixture of stereoisomers of the starting product.
USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS
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Page/Page column 47; 48; 54, (2014/07/08)
The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.