16825-16-4Relevant articles and documents
Discrimination of stereoisomers by one-dimensional 13C NMR: All 16 stereoisomers of 4-hydroxy-α-tocopherol resolved
Duchateau, Alexander L. L.,Lankhorst, Peter P.,Netscher, Thomas
, (2021/08/26)
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USING MIXTURES OF E/Z ISOMERS TO OBTAIN QUANTITATIVELY SPECIFIC PRODUCTS BY COMBINED ASYMMETRIC HYDROGENATIONS
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Page/Page column 58; 59, (2014/07/08)
The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.
PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS
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Page/Page column 55; 61, (2014/07/08)
The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.