168476-61-7Relevant articles and documents
Some synthetic approaches to ropinirole (SK and F 101468-A): A potent dopamine receptor agonist
Hayler,Howie,Giles,Negus,Oxley,Walsgrove,Walsh,Dagger,Fortunak,Mastrocola
, p. 875 - 882 (1995)
Three new routes to ropinirole (SK and F 101468-A, 1) are described each involving the preparation of 3-chlorooxindole intermediates of type 3 from β-nitrostyrenes as the pivotal step. The superiority of sulphonate esters 17a-c as direct precursors to 1 over the bromide 11 is also described.