Some synthetic approaches to ropinirole (SK and F 101468-A): A potent dopamine receptor agonist

DOI: 10.1002/jhet.5570320334

Source and publish data:

Journal of Heterocyclic Chemistry p. 875 - 882 (1995)

Update date:2022-08-03

Topics:

Authors:

Hayler Hayler

Howie Howie

Giles Giles

Negus Negus

Oxley Oxley

Walsgrove

Walsh Walsh

Dagger Dagger

Fortunak

Mastrocola

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570320334

Three new routes to ropinirole (SK and F 101468-A, 1) are described each involving the preparation of 3-chlorooxindole intermediates of type 3 from β-nitrostyrenes as the pivotal step. The superiority of sulphonate esters 17a-c as direct precursors to 1 over the bromide 11 is also described.

Full text of DOI:10.1002/jhet.5570320334

Products guided by the article

Product name:4-(2-acetoxyethyl)-1,3-dihydro-2H-indolin-2-one

Cas No:168476-61-7

R&D Labs maybe for 168476-61-7

Tradlon Chemical Co., Ltd.

Contact:+86-710-3516804

Address:Number 83,Panggong road,Xiangcheng District,Xiangyang ,Hubei
Suzhou SuKaiLu Chemical Technology Co., Ltd.

Contact:+86-512-62766020

Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
Pure Chemistry Scientific Inc.

Contact:+1-857-366-7588

Address:14905 SW freeway street #232, Sugarland, TX 77478, USA
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.

Contact:+86 532 80861829

Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.

Contact:+86-0150-58101658

Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China

Relevant to this article

Cyclization/hydrosilylation of functionalized 1,6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands

Doi:10.1021/jo015986p
(2002)
Palladium-Assisted Cyano Substitution Reactions of (PMe2Ph)2Pd(B9H9As2)and (PMe2Ph)2Pd(B9C2H11). X-ray Crystal and Molecular Structures of 5-CN-1,1-(PMe2Ph)2-closo-1,2,3-PdAs2B9H8, 1-(t)BuNC-5-CN-1-(PMe2Ph)-closo-1,2,3-PdAs2B9H8, and 4,5-(CN)2-1,1-(PMe2Ph

Doi:10.1021/ic00130a007
()
Doi:10.1021/jo01161a006
(1948)
Doi:10.1021/jo01273a047
(1968)
(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21- dimetheno-1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene- 1,3(2H)-dione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase Cβ

Doi:10.1021/jm950588y
(1996)
Copper-Catalyzed Domino Reactions for the Synthesis of Phenothiazines

Doi:10.1002/ejoc.201500667
(2015)

Article Doi