Some synthetic approaches to ropinirole (SK and F 101468-A): A potent dopamine receptor agonist

DOI: 10.1002/jhet.5570320334

Source and publish data:

Journal of Heterocyclic Chemistry p. 875 - 882 (1995)

Update date:2022-08-03

Topics:

Authors:

Hayler Hayler

Howie Howie

Giles Giles

Negus Negus

Oxley Oxley

Walsgrove

Walsh Walsh

Dagger Dagger

Fortunak

Mastrocola

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jhet.5570320334

Three new routes to ropinirole (SK and F 101468-A, 1) are described each involving the preparation of 3-chlorooxindole intermediates of type 3 from β-nitrostyrenes as the pivotal step. The superiority of sulphonate esters 17a-c as direct precursors to 1 over the bromide 11 is also described.

Full text of DOI:10.1002/jhet.5570320334

Products guided by the article

Product name:4-(2-acetoxyethyl)-1,3-dihydro-2H-indolin-2-one

Cas No:168476-61-7

R&D Labs maybe for 168476-61-7

SuZhou Yacoo Science Co., Ltd

Contact:86-512-87182055

Address:No.128 Fangzhou Rd, Suzhou Industrial Park, China, 215125, China
APOLLO HEALTHCARE RESOURCES

Contact:+65 9658 0999

Address:26 Sin Ming Lane, Midview City, #05-118, Singapore 573971
ALPHA PHARMACEUTICAL CO，LTD JIANGSU

Contact:+86-527-84829968,+86-527-84829998

Address:suqian city
Guarson Chemical Co., Ltd.

website:http://www.guarson.com

Contact:+86-523-88059600,+86-13805268803

Address:Room B1006,Yafang Building,Jiangyan Avenue,Jiangyan District, Taizhou City,Jiangsu,China
Shanghai Run-Biotech Co., Ltd.

website:http://www.run-biotech.com

Contact:+86-21-31576854/57171705 / 57171706

Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China

Relevant to this article

Cyclization/hydrosilylation of functionalized 1,6-diynes catalyzed by cationic platinum complexes containing bidentate nitrogen ligands

Doi:10.1021/jo015986p
(2002)
Palladium-Assisted Cyano Substitution Reactions of (PMe2Ph)2Pd(B9H9As2)and (PMe2Ph)2Pd(B9C2H11). X-ray Crystal and Molecular Structures of 5-CN-1,1-(PMe2Ph)2-closo-1,2,3-PdAs2B9H8, 1-(t)BuNC-5-CN-1-(PMe2Ph)-closo-1,2,3-PdAs2B9H8, and 4,5-(CN)2-1,1-(PMe2Ph

Doi:10.1021/ic00130a007
()
Doi:10.1021/jo01161a006
(1948)
Doi:10.1021/jo01273a047
(1968)
(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21- dimetheno-1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene- 1,3(2H)-dione (LY333531) and related analogues: Isozyme selective inhibitors of protein kinase Cβ

Doi:10.1021/jm950588y
(1996)
Copper-Catalyzed Domino Reactions for the Synthesis of Phenothiazines

Doi:10.1002/ejoc.201500667
(2015)

Article Doi