16883-74-2

Basic information

• Product Name: Benzenesulfinic acid, lithium salt
• CAS NO: 16883-74-2
• Molecular Formula: C6H6O2S.Li
• Molecular Weight: 148.112
• Mol File: 16883-74-2.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzenesulfinic acid, lithium salt(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfinic acid, lithium salt(16883-74-2)
• EPA Substance Registry System: Benzenesulfinic acid, lithium salt(16883-74-2)

Safety Data

• Hazardous Substances Data: 16883-74-2(Hazardous Substances Data)

Upstream product

• 109-72-8 n-butyllithium 
• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 591-51-5 phenyllithium 
• 98-80-6 phenylboronic acid 
• 71-43-2 benzene 
• 599-71-3 piloty's acid 
• 36649-96-4 lithium pentafluorobenzenesulfinate 
• 26186-79-8 mercuric benzenesulfinate 
• 4238-09-9 phenyl isopropyl sulfone 
• 108-98-5 thiophenol 
• 3052-45-7 allyllithium 
• 119814-58-3 (R)-4-((E)-3-Benzenesulfonylmethoxy-propenyl)-2,2-dimethyl-[1,3]dioxolane 
• 781-07-7 benzenesulfonic acid n-hexylester 
• 594-19-4 tert.-butyl lithium 

Downstream Products

• 35387-59-8 1,2-Bis(phenylsulfonyl)ethylene 
• 3112-85-4 methylphenylsulfonate 
• 127-63-9 diphenyl sulphone 
• 640-57-3 phenyltolylsulfone 
• 3112-82-1 (2,4,6-trimethylphenyl) phenyl sulfone 
• 2548-26-7 2,5-dimethyldiphenyl sulfone 
• 3112-84-3 4-methoxyphenyl phenyl sulfone 
• 80-00-2 4-Chlorophenyl phenyl sulfone 
• 1416262-12-8 1,3,5-triisopropyl-2-(phenylsulfonyl)benzene 
• 2715-05-1 1-(trifluoromethyl)-3-(phenylsulfonyl)benzene 
• 7018-84-0 phenyl o-tolyl sulfone 
• 59830-37-4 1-phenylsulfonyl-2-methyl-4-hydroxy-but-2-ene 
• 59830-43-2 1-hydroxy-3,7-dimethyl-4-(phenylsulfonyl)-9-(2,6,6-trimethylcyclohexen-1-yl)-none-2,6,8-triene 
• 16212-05-8 (allylsulfonyl)benzene 

Relevant articles and documents

Manganese(iii) acetate-mediated direct C(sp2)-H-sulfonylation of enamides with sodium and lithium sulfinates

A Mn(OAc)3 mediated oxidative C(sp2)-H sulfonylation of enamides and encarbamates with sodium and lithium sulfinates is reported. This operationally simple transformation provides a straightforward and highly stereoselective access to (E)-β-amidovinyl sulfones in moderate to excellent yields. The reaction proceeds readily under mild conditions at room temperature and tolerates various sensitive functional groups. This process affords exclusively (E)-configurated β-amidovinyl sulfones independent of the starting material configuration. Moreover, a direct transformation of organolithium reagents and sulfur dioxide into β-amidovinyl sulfones is described.

Nickel(II)-Catalyzed Synthesis of Sulfinates from Aryl and Heteroaryl Boronic Acids and the Sulfur Dioxide Surrogate DABSO

We report a redox-neutral Ni(II)-catalyzed sulfination of readily available aryl and heteroaryl boronic acids. Using the combination of commercially available, air-stable NiBr2·(glyme), a commercially available phenanthroline ligand, and DABSO, boronic acids are efficiently converted to the corresponding sulfinate salts, which can be further elaborated to valuable sulfonyl-containing groups, including sulfones, sulfonamides, sulfonyl fluorides, and sulfonate esters. The catalyst loading can be reduced to 2.5 mol ?% on a gram scale. This practically simple protocol tolerates an unprecedented range of pharmaceutically relevant and electron-poor (hetero)aryl boronic acids, allowing the direct synthesis of active pharmaceutical ingredients.

Manganese(III) Acetate Mediated C–H Sulfonylation of 1,4-Dimethoxybenzenes with Sodium and Lithium Sulfinates

A simple and mild Mn(OAc)3-promoted oxidative coupling of 1,4-dimethoxybenzenes with sodium and lithium sulfinates was developed. The reaction proceeded readily at room temperature in air, and various sulfones were synthesized in moderate to high yields. In addition, a straightforward approach for the conversion of organolithium reagents and sulfur dioxide into sulfonylated 1,4-dimethoxybenzenes was explored.