16913-46-5

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 97856-61-6 3-Ethoxycarbonylallylidenetriphenylarsorane 
• 37746-78-4 4-bromo-trans-crotonic acid ethyl ester 
• 49678-08-2 3-(4-nitrophenyl)-propenal 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 1530-45-6 (carbethoxymethyl)triphenylphosphonium bromide 
• 42516-28-9 ethyl (2E)-4-(diethoxyphosphoryl)crotonate 
• 97856-60-5 3-Ethoxycarbonylallylidenetriphenylarsonium bromide 

Downstream Products

• 711014-67-4 (2E,4E)-5-(4-aminophenyl)penta-2,4-dienoic acid ethyl ester 
• 711014-68-5 (2E,4E)-5-[4-(4-Methoxy-benzenesulfonylamino)-phenyl]-penta-2,4-dienoic acid ethyl ester 
• 49678-09-3 (2E,4E)-5-(4-nitrophenyl)-2,4-pentadienal 
• 206873-07-6 N-(2E,4E)-5-(4-nitrophenyl)penta-2,4-dienyltoluenesulfonamide 

Relevant academic research and scientific papers

SN2″-Selective and Enantioselective Substitution with Unsaturated Organoboron Compounds and Catalyzed by a Sulfonate-Containing NHC-Cu Complex

The first broadly applicable strategy for SN2″-selective and enantioselective catalytic substitution is disclosed. Transformations are promoted by 5.0 mol% of a sulfonate-containing NHC-Cu complex (NHC = N-heterocyclic carbene), and are carried

Facile Preparation of α-Cyano-α,ω-Diaryloligovinylenes: A New Class of Color-Tunable Solid Emitters

An efficient Knoevenagel condensation reaction was used to construct a series of α-cyano-α,ω-diaryloligovinylenes, which show prominent fluorescence emission in the solid state. On investigating the effect of conjugation length on fluorescent properties,

Efficient cleavage of the N-O bond of 3,6-dihydro-1,2-oxazines mediated by some α-hetero substituted carbonyl compounds in mild conditions

The efficient cleavage of the N-O bond of some nitroso Diels-Alder cycloadducts has been achieved in mild conditions, mediated either by 2,2-dimethyl-1,3-dioxan-5-one or 1,3-dithiolane-2-carboxaldehyde. These new and purely organic conditions allow an exc

PHARMACEUTICAL AGENTS

Use of compounds of formula (I) in the manufacture of a medicament for use in treating a disorder mediated by histone deacetylase: wherein the symbol ---- represents a single bond or a double bond or the symbol ---- R6 and R8 togethe

PYRROLYLPHENYL-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES

Disclosed are the pyrrolylphenyl-substituted hydroxamic acid derivatives of the formula wherein R represents hydrogen, lower alkyl, halogen or lower alkoxy; R1 and R2 independently represent hydrogen, lower alkyl or aryl; Y represents a direct bond, lower alkylene, lower alkenylene, lower alkadienylene, (thio, sulfinyl or sulfonyl)-lower alkylene or oxy-lower alkylene; Z represents wherein R3 represents hydrogen or acyl; R4 represents lower alkyl, C3-C7-cycloalkyl, aryl or aryl-lower alkyl; or Z represents wherein R3 represents hydrogen or acyl; R5 represents lower alkyl, C3-C7-cycloalkyl, aryl, aryl-lower alkyl, amino or N-(mono-or di-lower alkyl)-amino; R6 and R7 represent hydrogen or lower alkyl; and pharmaceutically acceptable salts thereof provided that R3 represents hydrogen; which are useful as selective lipoxygenase inhibitors, methods for preparation thereof, pharmaceutical compositions comprising said compounds, and a method of inhibiting lipoxygenase and of treating diseases in mammals which are responsive to lipoxygenase inhibition using said compounds and pharmaceutical compositions comprising said compounds of the invention.