16913-58-9

Upstream product

• 110-91-8 morpholine 
• 16911-89-0 phenyl chlorodithioformate 
• 3581-30-4 morpholine-4-carbodithioic acid 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 75-15-0 carbon disulfide 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 66003-76-7 Diphenyliodonium triflate 
• 67-66-3 chloroform 
• 14001-56-0 sodium phenylsulfanesulfonate 
• 591-50-4 iodobenzene 
• 59534-02-0 chloro-phenylsulfanyl-(toluene-4-sulfonyl)-methanesulfenyl chloride 
• 72087-89-9 C₁₆H₁₅ClO₃S₄ 

Downstream Products

• 51861-57-5 S-phenyl morpholine-4-carbothioate 

Relevant academic research and scientific papers

Aryne Three-Component Coupling Involving CS2for the Synthesis of S-Aryl Dithiocarbamates

A facile synthesis of biologically important S-aryl dithiocarbamates has been demonstrated by the aryne three-component coupling involving CS2 and aliphatic amines. This transition-metal-free and mild reaction is scalable and operates with good functional group compatibility. Preliminary mechanistic experiments, including density functional theory studies, are also provided. Moreover, with 3-triflyloxybenzynes, a unique four-component coupling incorporating tetrahydrofuran was observed.

Multicomponent Synthesis of Biologically Relevant S-Aryl Dithiocarbamates Using Diaryliodonium Salts

A transition-metal-free one-pot three-component annulation between diaryliodonium triflates, cyclic and acyclic aliphatic amines, and carbon disulfide providing a convenient and efficient access to biologically relevant S-aryl dithiocarbamates is developed. The reaction does not require metal, base, or any other additive and operates under mild and ambient conditions. This methodology is robust, scalable, and exhibits a broad substrate scope. The in silico analysis revealed that the majority of the compounds have a drug-likeness and good ADMET characteristics.

Magnetically recyclable sepiolite/iron oxide/cupric oxide nanocomposite as a novel catalyst for the synthesis of S-aryl dithiocarbamates by C-S bond formation

A convenient and efficient procedure is described for the synthesis of S-aryl dithiocarbamates by C-S bond formation through the coupling reaction of three components between secondary amines, carbon disulfide, and aryl iodides using magnetically separabl

Thiocarbonyl Surrogate via Combination of Potassium Sulfide and Chloroform for Dithiocarbamate Construction

An efficient and practical thiocarbonyl surrogate via combination of potassium sulfide and chloroform was established. A variety of dithiocarbamates were afforded along with four new chemical bond formations in a one-pot reaction in which the thiocarbonyl

Eco-compatible three component strategies for C-S bond formation in thioether and S-aryl-carbamodithioate compounds catalyzed by copper(II) nanoparticles supported on modified AlPO4

One-pot and three components C-S bond formation reactions in thioethers and S-aryl-carbamodithioates have been catalyzed by a copper heterogeneous nano-catalyst supported on modified AlPO4 under different reaction conditions. The above-mentioned nano-catalyst has been characterized by various techniques such as SEM, TEM, AFM, XRD, FT-IR, UV–Vis, CV, BET, TGA, ICP and XPS spectrometry and its particle size was estimated to be between 60–110?nm. Finally, the reusability of the catalyst up to ten cycles without any significant leaching is one of the outstanding properties of the catalyst.

A magnetically recyclable iron oxide-supported copper oxide nanocatalyst (Fe3O4-CuO) for one-pot synthesis of: S -aryl dithiocarbamates under solvent-free conditions

A green, convenient and efficient procedure is reported for the synthesis of S-aryl dithiocarbamates by a simple one-pot three component Ullmann-type condensation of an amine, carbon disulfide and an aryl iodide. Magnetically separable and reusable copper

Transition metal-free procedure for the synthesis of S-aryl dithiocarbamates using aryl diazonium fluoroborate in water at room temperature

A convenient, efficient and green procedure for the synthesis of S-aryl dithiocarbamates has been developed by a simple one-pot condensation of aryl diazonium fluoroborate, carbon disulfide and amine in the absence of any transition metal catalyst in water at room temperature. The reactions of a variety of substituted aryl diazonium fluoroborates, and cyclic and open chain amines, have been addressed. The products are purified by crystallization from ethanol and the process does not involve any hazardous solvent.

Kinetics and mechanism of the reactions of aryl chlorodithioformates with pyridines and secondary alicyclic amines

The reactions of pyridines and secondary alicyclic (SA) amines with phenyl and 4-nitrophenyl chlorodithioformates (PClDTF and NPClDTF, respectively) are subjected to a kinetic study in aqueous ethanol (44 wt% ethanol) solution, at 25.0 ° C, and an ionic s

STUDIES OF DITHIIRANES AND THIOSULFINES AS REACTIVE INTERMEDIATES

Indirect, but compelling evidence for the intermediacy of dithiiranes 1 and thiosulfines 2 has been found by us and is also provided by literature data.The intriguing dithiirane -> dithioester rearrangement as well as most of the interrelations and conversions postulated in Scheme 1 have been demonstrated experimentally.In a number of cases acetyl α-chloroalkyl disulfides 16 (X=Cl, Y=COCH3) are useful starting materials for the synthesis of thioamides such as 40.